Anti-CTSZ Antibody (CAB2681)
- SKU:
- CAB2681
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CTSZ Antibody |
| 抗体コード: | CAB2681 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human CTSZ (NP_001327.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | SKOV3, 22Rv1, SW480, THP-1, HeLa, Mouse kidney, Mouse liver, Rat thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human CTSZ (NP_001327.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MARR GPGW RPLL LLVL LAGA AQGG LYFR RGQT CYRP LRGD GLAP LGRS TYPR PHEY LSPA DLPK SWDW RNVD GVNY ASIT RNQH IPQY CGSC WAHA STSA MADR INIK RKGA WPST LLSV QNVI DCGN AGSC EGGN DLSV WDYA HQHG IPDE TCNN YQAK DQEC DKFN QCGT CNEF KECH AIRN YTLW RVGD YGSL SGRE KMMA EIYA NGPI SCGI MATE RLAN YTGG IYAE YQDT TYIN HVVS VAGW GISD GTEY WIVR NSWG EPWG ERGW LRIV TSTY KDGK GARY NLAI EEHC TFGD PIV |
| 遺伝子ID: | 1522 |
| Uniprot: | Q9UBR2 |
| セルラーロケーション: | Lysosome |
| 計算された分子量: | 33kDa |
| 観察された分子量: | 36kDa |
| 同義語: | CTSZ, CTSX |
| バックグラウンド: | The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. |
| UniProt Protein Function: | CTSZ: Exhibits carboxy-monopeptidase as well as carboxy- dipeptidase activity. Belongs to the peptidase C1 family. |
| UniProt Protein Details: | Protein type:EC 3.4.18.1; Protease Chromosomal Location of Human Ortholog: 20q13.32 Cellular Component: extracellular space; intracellular membrane-bound organelle; lysosome; endoplasmic reticulum; plasma membrane Molecular Function:cysteine-type peptidase activity Biological Process: cellular protein metabolic process; angiotensin maturation; proteolysis Disease: Mycobacterium Tuberculosis, Susceptibility To |
| NCBI Summary: | The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. [provided by RefSeq, Oct 2008] |
| UniProt Code: | Q9UBR2 |
| NCBI GenInfo Identifier: | 12643324 |
| NCBI Gene ID: | 1522 |
| NCBI Accession: | Q9UBR2.1 |
| UniProt Secondary Accession: | Q9UBR2,O75331, Q9UQV5, Q9UQV6, B2RC40, |
| UniProt Related Accession: | Q9UBR2 |
| Molecular Weight: | 303 |
| NCBI Full Name: | Cathepsin Z |
| NCBI Synonym Full Names: | cathepsin Z |
| NCBI Official Symbol: | CTSZ |
| NCBI Official Synonym Symbols: | CTSX |
| NCBI Protein Information: | cathepsin Z; cathepsin P; cathepsin X; cathepsin Y; cathepsin B2; cathepsin IV; cathepsin Z1; preprocathepsin P; carboxypeptidase LB; lysosomal carboxypeptidase B; cysteine-type carboxypeptidase |
| UniProt Protein Name: | Cathepsin Z |
| UniProt Synonym Protein Names: | Cathepsin P; Cathepsin X |
| Protein Family: | Cathepsin |
| UniProt Gene Name: | CTSZ |
| UniProt Entry Name: | CATZ_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CTSZ antibody (CAB2681) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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