Anti-CREBBP Antibody (CAB17096)
- SKU:
- CAB17096
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CREBBP Antibody |
| 抗体コード: | CAB17096 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of mouse CREBBP. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | Recombinant protein of mouse CREBBP. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 12914 |
| Uniprot: | Q6GQV9 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 172kDa |
| 観察された分子量: | 290kDa |
 | Western blot - CREBBP Rabbit pAb (CAB17096) |
| 同義語: | CREBBP, CBP, KAT3A, RSTS, RSTS1 |
| バックグラウンド: | This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Code: | Q6GQV9 |
| NCBI GenInfo Identifier: | 81884771 |
| NCBI Gene ID: | 12914 |
| NCBI Accession: | |
| UniProt Related Accession: | P45481 |
| Molecular Weight: | 172kDa |
| NCBI Full Name: | Crebbp protein |
| NCBI Synonym Full Names: | CREB binding protein |
| NCBI Official Symbol: | Crebbp |
| NCBI Official Synonym Symbols: | CBP; KAT3A; AW558298; CBP/p300; p300/CBP |
| NCBI Protein Information: | CREB-binding protein |
| UniProt Protein Name: | |
| Protein Family: | CREB-binding protein |
| UniProt Gene Name: |