Anti-CPB1 Antibody (CAB10486)

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SKU:
CAB10486
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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Description

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抗体名:Anti-CPB1 Antibody
抗体コード:CAB10486
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 111-417 of human CPB1 (NP_001862.2).
申し込み:WB
推奨希釈:WB 1:1000 - 1:2000
反応性:Human, Mouse, Rat
ポジティブサンプル:SW620, Mouse pancreas, Mouse liver, Mouse spleen, Rat pancreas
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 111-417 of human CPB1 (NP_001862.2).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:ATGH SYEK YNKW ETIE AWTQ QVAT ENPA LISR SVIG TTFE GRAI YLLK VGKA GQNK PAIF MDCG FHAR EWIS PAFC QWFV REAV RTYG REIQ VTEL LDKL DFYV LPVL NIDG YIYT WTKS RFWR KTRS THTG SSCI GTDP NRNF DAGW CEIG ASRN PCDE TYCG PAAE SEKE TKAL ADFI RNKL SSIK AYLT IHSY SQMM IYPY SYAY KLGE NNAE LNAL AKAT VKEL ASLH GTKY TYGP GATT IYPA AGGS DDWA YDQG IRYS FTFE LRDT GRYG FLLP ESQI RATC EETF LAIK YVAS YVLE HLY
遺伝子ID:1360
Uniprot:P15086
セルラーロケーション:Secreted
計算された分子量:47kDa
観察された分子量:47kDa
同義語:CPB1, CPB, PASP, PCPB
バックグラウンド:Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma.
UniProt Protein Function:CPB1: Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted; EC 3.4.17.2; Protease

Chromosomal Location of Human Ortholog: 3q24

Cellular Component: extracellular region

Molecular Function:carboxypeptidase activity; zinc ion binding; metallocarboxypeptidase activity

Biological Process: proteolysis

NCBI Summary:Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008]
UniProt Code:P15086
NCBI GenInfo Identifier:20532382
NCBI Gene ID:1360
NCBI Accession:P15086.4
UniProt Secondary Accession:P15086,O60834, Q53XJ0, Q96BQ8,
UniProt Related Accession:P15086
Molecular Weight:47,368 Da
NCBI Full Name:Carboxypeptidase B
NCBI Synonym Full Names:carboxypeptidase B1 (tissue)
NCBI Official Symbol:CPB1  
NCBI Official Synonym Symbols:CPB; PASP; PCPB  
NCBI Protein Information:carboxypeptidase B; pancreas-specific protein; pancreatic carboxypeptidase B; procarboxypeptidase B; protaminase; tissue carboxypeptidase B
UniProt Protein Name:Carboxypeptidase B
UniProt Synonym Protein Names:Pancreas-specific protein; PASP
UniProt Gene Name:CPB1  
UniProt Entry Name:CBPB1_HUMAN
Anti-CPB1 Antibody (CAB10486)Western blot analysis of extracts of various cell lines, using CPB1 antibody (CAB10486) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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