Anti-COL15A1 Antibody (CAB16820)
- SKU:
- CAB16820
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-COL15A1 Antibody |
| 抗体コード: | CAB16820 |
| 抗体サイズ: | 20uL, 50 uL |
| 申し込み: | IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-450 of human COL15A1 (NP_001846.3). |
| 申し込み: | IHC |
| 推奨希釈: | IHC 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-450 of human COL15A1 (NP_001846.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AGIF MGNA GATG LERF TGSL QQLT VHPD PRTP EELC DPEE SSAS GETS GLQE ADGV AEIL EAVT YTQA SPKE AKVE PINT PPTP SSPF EDME LSGE PVPE GTLE TTNM SIIQ HSSP KQGS GEIL NDTL EGVH SVDG DPIT DSGS GAGA FLDI AEEK NLAA TAAG LAEV PIST AGEA EASS VPTG GPTL SMST ENPE EGVT PGPD NEER LAAT AAGE AEAL ASMP GEVE ASGV APGE LDLS MSAQ SLGE EAT |
| 遺伝子ID: | 1306 |
| Uniprot: | P39059 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | Refer to figures |
| 同義語: | COL15A1 |
| バックグラウンド: | This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration. |
| UniProt Protein Function: | COL15A1: Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle. Belongs to the multiplexin collagen family. |
| UniProt Protein Details: | Protein type:Secreted; Extracellular matrix; Secreted, signal peptide Chromosomal Location of Human Ortholog: 9q21-q22 Cellular Component: extracellular matrix; extracellular space; endoplasmic reticulum lumen; collagen type XV; integral to membrane; extracellular region Molecular Function:extracellular matrix structural constituent Biological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; angiogenesis; signal transduction; cell differentiation; cell adhesion |
| NCBI Summary: | This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration. [provided by RefSeq, May 2013] |
| UniProt Code: | P39059 |
| NCBI GenInfo Identifier: | 119579308 |
| NCBI Gene ID: | 1306 |
| NCBI Accession: | EAW58904.1 |
| UniProt Secondary Accession: | P39059,Q5T6J4, Q9UDC5, Q9Y4W4, |
| UniProt Related Accession: | P39059 |
| Molecular Weight: | 141,720 Da |
| NCBI Full Name: | collagen, type XV, alpha 1, isoform CRA_f |
| NCBI Synonym Full Names: | collagen, type XV, alpha 1 |
| NCBI Official Symbol: | COL15A1 |
| NCBI Protein Information: | collagen alpha-1(XV) chain; collagen alpha-1(XV) chain; restin; endostatin-XV; collagen type XV proteoglycan; collagen XV, alpha-1 polypeptide |
| UniProt Protein Name: | Collagen alpha-1(XV) chain |
| UniProt Synonym Protein Names: | Endostatin-XV; Related to endostatin; Restin-IRestin-2; Alternative name(s):; Restin-IIRestin-3; Alternative name(s):; Restin-IIIRestin-4; Alternative name(s):; Restin-IV |
| Protein Family: | Zinc finger protein CONSTANS |
| UniProt Gene Name: | COL15A1 |
| UniProt Entry Name: | COFA1_HUMAN |