Anti-COL11A2 Antibody (CAB10473)
- SKU:
- CAB10473
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-COL11A2 Antibody |
抗体コード: | CAB10473 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-380 of human COL11A2 (NP_542411.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A375, HepG2, K-562 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-380 of human COL11A2 (NP_542411.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | IVPG VQAA YESC EQKE LECE GGQR ERPQ NQQP HRAQ RSPQ QQPS RLHR PQNQ EPQS QPTE SLYY DYEP PYYD VMTT GTTP DYQD PTPG EEEE ILES SLLP PLEE EQTD LQVP PTAD RFQA EEYG EGGT DPPE GPYD YTYG YGDD YREE TELG PALS AETA HSGA AAHG PRG |
遺伝子ID: | 1302 |
Uniprot: | P13942 |
セルラーロケーション: | Secreted, extracellular matrix, extracellular space |
計算された分子量: | 31kDa/159-171kDa |
観察された分子量: | 150kDa |
同義語: | COL11A2, DFNA13, DFNB53, FBCG2, HKE5, PARP, STL3 |
バックグラウンド: | This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6. |
UniProt Protein Function: | May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. |
NCBI Summary: | This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6. [provided by RefSeq, Jul 2009] |
UniProt Code: | P13942 |
NCBI GenInfo Identifier: | 374095517 |
NCBI Gene ID: | 1302 |
NCBI Accession: | P13942.5 |
UniProt Secondary Accession: | P13942,Q07751, Q13271, Q13272, Q13273, Q5JP94, Q5SUI8 Q7Z6C3, Q99866, Q9UIP9, A6NLX2, E7ER90, |
UniProt Related Accession: | P13942 |
Molecular Weight: | 172kDa |
NCBI Full Name: | Collagen alpha-2(XI) chain |
NCBI Synonym Full Names: | collagen type XI alpha 2 chain |
NCBI Official Symbol: | COL11A2 |
NCBI Official Synonym Symbols: | HKE5; PARP; STL3; FBCG2; DFNA13; DFNB53 |
NCBI Protein Information: | collagen alpha-2(XI) chain |
UniProt Protein Name: | Collagen alpha-2(XI) chain |
Protein Family: | Collagen |
UniProt Gene Name: | COL11A2 |
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