Anti-CLDN2 Antibody (CAB14085)
- SKU:
- CAB14085
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CLDN2 Antibody |
| 抗体コード: | CAB14085 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human CLDN2 (NP_001164566.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse liver, Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human CLDN2 (NP_001164566.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | WKTS SYVG ASIV TAVG FSKG LWME CATH STGI TQCD IYST LLGL PADI QAAQ AMMV TSSA ISSL ACII SVVG MRCT VFCQ ESRA KDRV AVAG GVFF ILGG LLGF IPVA WNLH GILR DFYS PLVP DSMK FEIG EALY LGII SSLF SLIA GIIL CFSC SSQR NRSN YYDA YQAQ PLAT RSSP RPGQ PPKV KSEF NSYS LTGY V |
| 遺伝子ID: | 9075 |
| Uniprot: | P57739 |
| セルラーロケーション: | Cell junction, Cell membrane, Multi-pass membrane protein, tight junction |
| 計算された分子量: | 24kDa |
| 観察された分子量: | 25kDa |
| 同義語: | CLDN2, claudin-2 |
| バックグラウンド: | This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. |
| UniProt Protein Function: | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. |
| NCBI Summary: | This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010] |
| UniProt Code: | P57739 |
| NCBI GenInfo Identifier: | 12229749 |
| NCBI Gene ID: | 9075 |
| NCBI Accession: | P57739.1 |
| UniProt Secondary Accession: | P57739,B2R6B9, |
| UniProt Related Accession: | P57739 |
| Molecular Weight: | 25kDa |
| NCBI Full Name: | Claudin-2 |
| NCBI Synonym Full Names: | claudin 2 |
| NCBI Official Symbol: | CLDN2 |
| NCBI Protein Information: | claudin-2 |
| UniProt Protein Name: | Claudin-2 |
| UniProt Synonym Protein Names: | SP82 |
| Protein Family: | Claudin |
| UniProt Gene Name: | CLDN2 |
 | Western blot analysis of extracts of various cell lines, using CLDN2 Antibody (CAB14085) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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