| NCBI Summary: | The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Alternative splicing results in multiple transcript variants. The longer transcripts, also known as 'Cenexins', encode proteins with a C-terminal extension that are differentially targeted to somatic centrioles and thought to be crucial for the formation of microtubule organizing centers. [provided by RefSeq, Oct 2010] |
| UniProt Code: | Q5BJF6 |
| NCBI GenInfo Identifier: | 24430181 |
| NCBI Gene ID: | 4957 |
| NCBI Accession: | NP_002531 |
| UniProt Related Accession: | Q5BJF6 |
| Molecular Weight: | 89kDa |
| NCBI Full Name: | outer dense fiber protein 2 isoform 9 |
| NCBI Synonym Full Names: | outer dense fiber of sperm tails 2 |
| NCBI Official Symbol: | ODF2 |
| NCBI Official Synonym Symbols: | CT134; ODF84; ODF2/1; ODF2/2 |
| NCBI Protein Information: | outer dense fiber protein 2 |
| UniProt Protein Name: | Outer dense fiber protein 2 |
| UniProt Synonym Protein Names: | Cenexin; Outer dense fiber of sperm tails protein 2 |
| Protein Family: | Outer dense fiber protein |
| UniProt Gene Name: | ODF2 |
| UniProt Entry Name: | ODFP2_HUMAN |
