Anti-CBX6 Antibody (CAB5533)
- SKU:
- CAB5533
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-CBX6 Antibody |
| 抗体コード: | CAB5533 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human CBX6 (NP_055107.3). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human CBX6 (NP_055107.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LLKA RAQA EALR ISDV HFSV KPSA SASS PKLH SSAA VHRL KKDI RRCH RMSR RPLP RPDP QGGS PGLR PPIS PFSE TVRI INRK VKPR EPKR NRII LNLK V |
| 遺伝子ID: | 23466 |
| Uniprot: | O95503 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 43kDa |
| 観察された分子量: | 50kDa |
| 同義語: | CBX6 |
| バックグラウンド: |
| UniProt Protein Function: | CBX6: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
| UniProt Protein Details: | Protein type:Transcription regulation Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: nucleoplasm; heterochromatin; PcG protein complex; nucleus Molecular Function:protein binding; single-stranded RNA binding Biological Process: transcription, DNA-dependent; chromatin modification; negative regulation of transcription from RNA polymerase II promoter |
| UniProt Code: | O95503 |
| NCBI GenInfo Identifier: | 17433289 |
| NCBI Gene ID: | 23466 |
| NCBI Accession: | O95503.1 |
| UniProt Secondary Accession: | O95503,Q96EM5, A8KAH0, |
| UniProt Related Accession: | O95503 |
| Molecular Weight: | 412 |
| NCBI Full Name: | Chromobox protein homolog 6 |
| NCBI Synonym Full Names: | chromobox homolog 6 |
| NCBI Official Symbol: | CBX6 |
| NCBI Protein Information: | chromobox protein homolog 6 |
| UniProt Protein Name: | Chromobox protein homolog 6 |
| Protein Family: | Chromobox protein |
| UniProt Gene Name: | CBX6 |
| UniProt Entry Name: | CBX6_HUMAN |
 | Western blot analysis of extracts of HeLa cells, using CBX6 antibody (CAB5533) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
 | Immunohistochemistry of paraffin-embedded rat liver using CBX6 antibody (CAB5533) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat brain using CBX6 antibody (CAB5533) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse testis using CBX6 antibody (CAB5533) at dilution of 1:100 (40x lens). |
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