Anti-CAPZA1 Antibody (CAB3776)
- SKU:
- CAB3776
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CAPZA1 Antibody |
| 抗体コード: | CAB3776 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA1 (NP_006126.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:1000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, Jurkat, MCF7, HL-60, Mouse brain, Mouse kidney, Mouse lung, Rat lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA1 (NP_006126.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MADF DDRV SDEE KVRI AAKF ITHA PPGE FNEV FNDV RLLL NNDN LLRE GAAH AFAQ YNMD QFTP VKIE GYED QVLI TEHG DLGN SRFL DPRN KISF KFDH LRKE ASDP QPEE ADGG LKSW RESC DSAL RAYV KDHY SNGF CTVY AKTI DGQQ TIIA CIES HQFQ PKNF WNGR WRSE WKFT ITPP TAQV VGVL KIQV HYYE DGNV QLVS HKDV QDSL TVSN EAQT AKEF IKII ENAE NEYQ TAIS ENYQ TMSD TTFK ALRR QLPV TRTK IDWN KILS YKIG KEMQ NA |
| 遺伝子ID: | 829 |
| Uniprot: | P52907 |
| セルラーロケーション: | Cytoplasm, cytoskeleton |
| 計算された分子量: | 32kDa |
| 観察された分子量: | 38kDa |
| 同義語: | CAPZA1, CAPPA1, CAPZ, CAZ1 |
| バックグラウンド: | CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. |
| UniProt Protein Function: | CAPZA1: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Belongs to the F-actin-capping protein alpha subunit family. |
| UniProt Protein Details: | Protein type:Actin-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 1p13.2 Cellular Component: F-actin capping protein complex; cytoskeleton; extracellular region; cytosol; actin cytoskeleton Molecular Function:protein binding; actin binding Biological Process: innate immune response; protein complex assembly; cell motility; blood coagulation; barbed-end actin filament capping |
| NCBI Summary: | CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P52907 |
| NCBI GenInfo Identifier: | 1705650 |
| NCBI Gene ID: | 829 |
| NCBI Accession: | P52907.3 |
| UniProt Secondary Accession: | P52907,Q53FQ6, Q6FHD5, |
| UniProt Related Accession: | P52907 |
| Molecular Weight: | 286 |
| NCBI Full Name: | F-actin-capping protein subunit alpha-1 |
| NCBI Synonym Full Names: | capping protein (actin filament) muscle Z-line, alpha 1 |
| NCBI Official Symbol: | CAPZA1 |
| NCBI Official Synonym Symbols: | CAPZ; CAZ1; CAPPA1 |
| NCBI Protein Information: | F-actin-capping protein subunit alpha-1; Cap Z; capZ alpha-1 |
| UniProt Protein Name: | F-actin-capping protein subunit alpha-1 |
| UniProt Synonym Protein Names: | CapZ alpha-1 |
| Protein Family: | F-actin-capping protein |
| UniProt Gene Name: | CAPZA1 |
| UniProt Entry Name: | CAZA1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CAPZA1 antibody (CAB3776) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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