Anti-CACNG7 Antibody (CAB7989)
- SKU:
- CAB7989
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | CACNG7 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB7989 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 156-275 of human CACNG7 (NP_114102.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, HepG2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 156-275 of human CACNG7 (NP_114102.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | INDE VMNR PSSS EQYF HYRY GWSF AFAA SSFL LKEG AGVM SVYL FTKR YAEE EMYR PHPA FYRP RLSD CSDY SGQF LQPE AWRR GRSP SDIS SDVS IQMT QNYP PAIK YPDH LHIS TSPC |
| 遺伝子ID: | 59284 |
| Uniprot: | P62955 |
| セルラーロケーション: | Membrane, Multi-pass membrane protein |
| 計算された分子量: | 31kDa |
| 観察された分子量: | 45kDa |
| 同義語: | CACNG7 |
| バックグラウンド: | The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. |
| UniProt Protein Function: | CACNG7: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity only for GRIA1 and GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Channel, calcium; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.4 Cellular Component: plasma membrane Molecular Function:channel regulator activity; voltage-gated calcium channel activity Biological Process: transmission of nerve impulse |
| NCBI Summary: | The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010] |
| UniProt Code: | P62955 |
| NCBI GenInfo Identifier: | 109730502 |
| NCBI Gene ID: | 59284 |
| NCBI Accession: | BC113503 |
| UniProt Secondary Accession: | P62955,Q52LL8, Q8VBX3, Q8WXS6, Q9BXT1, |
| UniProt Related Accession: | P62955 |
| Molecular Weight: | 31,003 Da |
| NCBI Full Name: | Homo sapiens calcium channel, voltage-dependent, gamma subunit 7, mRNA |
| NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit gamma 7 |
| NCBI Official Symbol: | CACNG7 |
| NCBI Protein Information: | voltage-dependent calcium channel gamma-7 subunit |
| UniProt Protein Name: | Voltage-dependent calcium channel gamma-7 subunit |
| UniProt Synonym Protein Names: | Neuronal voltage-gated calcium channel gamma-7 subunit; Transmembrane AMPAR regulatory protein gamma-7; TARP gamma-7 |
| Protein Family: | Voltage-dependent calcium channel |
| UniProt Gene Name: | CACNG7 |
| UniProt Entry Name: | CCG7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CACNG7 antibody (CAB7989) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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