Anti-ANXA11 Antibody (CAB7423)
- SKU:
- CAB7423
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-ANXA11 Antibody |
| 抗体コード: | CAB7423 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF IP |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 276-505 of human ANXA11 (NP_001148.1). |
| 申し込み: | WB IF IP |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-431, HT-29, Jurkat, SKOV3, A-549, Mouse brain, Mouse skeletal muscle, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 276-505 of human ANXA11 (NP_001148.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FDIY EIKE AIKG VGTD EACL IEIL ASRS NEHI RELN RAYK AEFK KTLE EAIR SDTS GHFQ RLLI SLSQ GNRD ESTN VDMS LAQR DAQE LYAA GENR LGTD ESKF NAVL CSRS RAHL VAVF NEYQ RMTG RDIE KSIC REMS GDLE EGML AVVK CLKN TPAF FAER LNKA MRGA GTKD RTLI RIMV SRSE TDLL DIRS EYKR MYGK SLYH DISG DTSG DYRK ILLK ICGG ND |
| 遺伝子ID: | 311 |
| Uniprot: | P50995 |
| セルラーロケーション: | Cytoplasm, Melanosome, Nucleus, Nucleus envelope, cytoskeleton, nucleoplasm, spindle |
| 計算された分子量: | 51kDa/54kDa |
| 観察された分子量: | 56kDa |
| 同義語: | ANXA11, ANX11, CAP50 |
| バックグラウンド: | This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. |
| UniProt Protein Function: | ANXA11: a calcium/phospholipid-binding protein found throughout the nucleoplasm at interphase and at the mitotic phase is concentrated at the loop-like structure around the mitotic apparatus. May interact with calcyclin (S100A6) in vivo. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion. |
| UniProt Protein Details: | Protein type:Nuclear envelope; Lipid-binding; Calcium-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 10q23 Cellular Component: nucleoplasm; azurophil granule; specific granule; membrane; cytoplasm; melanosome; spindle; nuclear envelope; phagocytic vesicle; midbody Molecular Function:protein binding; phosphatidylethanolamine binding; calcium-dependent phospholipid binding; calcium ion binding; calcium-dependent protein binding Biological Process: response to calcium ion; phagocytosis |
| NCBI Summary: | This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, May 2013] |
| UniProt Code: | P50995 |
| NCBI GenInfo Identifier: | 1703322 |
| NCBI Gene ID: | 311 |
| NCBI Accession: | P50995.1 |
| UniProt Secondary Accession: | P50995,B4DVE7, |
| UniProt Related Accession: | P50995 |
| Molecular Weight: | 51,242 Da |
| NCBI Full Name: | Annexin A11 |
| NCBI Synonym Full Names: | annexin A11 |
| NCBI Official Symbol: | ANXA11 |
| NCBI Official Synonym Symbols: | ANX11; CAP50 |
| NCBI Protein Information: | annexin A11; CAP-50; annexin XI; annexin-11; 56 kDa autoantigen; autoantigen, 56-kD; calcyclin-associated annexin 50 |
| UniProt Protein Name: | Annexin A11 |
| UniProt Synonym Protein Names: | 56 kDa autoantigen; Annexin XI; Annexin-11; Calcyclin-associated annexin 50; CAP-50 |
| Protein Family: | Annexin |
| UniProt Gene Name: | ANXA11 |
| UniProt Entry Name: | ANX11_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ANXA11 antibody (CAB7423) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunofluorescence analysis of A549 cells using ANXA11 antibody (CAB7423). Blue: DAPI for nuclear staining. |
 | Immunoprecipitation analysis of 200ug extracts of Jurkat cells, using 3 ug ANXA11 antibody (CAB7423). Western blot was performed from the immunoprecipitate using ANXA11 antibody (CAB7423) at a dilition of 1:1000. |
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