Anti-ANKRD13A Antibody (CAB10416)
- SKU:
- CAB10416
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ANKRD13A Antibody |
| 抗体コード: | CAB10416 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ANKRD13A (NP_149112.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | MCF7, HL-60 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ANKRD13A (NP_149112.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSSA CDAG DHYP LHLL VWKN DYRQ LEKE LQGQ NVEA VDPR GRTL LHLA VSLG HLES ARVL LRHK ADVT KENR QGWT VLHE AVST GDPE MVYT VLQH RDYH NTSM ALEG VPEL LQKI LEAP DFYV QMKW EFTS WVPL VSRI CPND VCRI WKSG AKLR VDIT LLGF ENMS WIRG RRSF IFKG EDNW AELM EVNH DDKV VTTE RFDL SQEM ERLT LDLM KPKS REVE RRLT SPVI NTSL DTKN |
| 遺伝子ID: | 88455 |
| Uniprot: | Q8IZ07 |
| セルラーロケーション: | Cell membrane, Late endosome |
| 計算された分子量: | 67kDa |
| 観察された分子量: | 71kDa |
| 同義語: | ANKRD13A, ANKRD13, NY-REN-25 |
| バックグラウンド: |
| UniProt Protein Function: | ANKRD13: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand- activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. Interacts (via the UIM 3 and 4 repeats) with EGFR (ubiquitinated); the interaction is direct, inhibited by ANKRD13A monoubiquitination and may regulate EGFR internalization |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 12q24.11 Cellular Component: late endosome; plasma membrane |
| UniProt Code: | Q8IZ07 |
| NCBI GenInfo Identifier: | 145559439 |
| NCBI Gene ID: | 88455 |
| NCBI Accession: | Q8IZ07.3 |
| UniProt Secondary Accession: | Q8IZ07,O60736, |
| UniProt Related Accession: | Q8IZ07 |
| Molecular Weight: | 67,619 Da |
| NCBI Full Name: | Ankyrin repeat domain-containing protein 13A |
| NCBI Synonym Full Names: | ankyrin repeat domain 13A |
| NCBI Official Symbol: | ANKRD13A |
| NCBI Official Synonym Symbols: | ANKRD13; NY-REN-25 |
| NCBI Protein Information: | ankyrin repeat domain-containing protein 13A; NY-REN-25 antigen |
| UniProt Protein Name: | Ankyrin repeat domain-containing protein 13A |
| UniProt Synonym Protein Names: | Protein KE03 |
| Protein Family: | Ankyrin repeat domain-containing protein |
| UniProt Gene Name: | ANKRD13A |
| UniProt Entry Name: | AN13A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ANKRD13A antibody (CAB10416) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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