Anti-AMOTL1 Antibody (CAB18112)
- SKU:
- CAB18112
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
抗体名: | Anti-AMOTL1 Antibody |
抗体コード: | CAB18112 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant protein of human AMOTL1. |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, MCF7, Mouse heart, Mouse lung, Mouse brain, Rat lung, Rat heart |
免疫原: | Recombinant protein of human AMOTL1. |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 154810 |
Uniprot: | Q8IY63 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | 107kDa |
同義語: | JEAP, AMOTL1 |
バックグラウンド: |
UniProt Protein Function: | Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. |
NCBI Summary: | The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
UniProt Code: | Q8IY63 |
NCBI GenInfo Identifier: | 666335625 |
NCBI Gene ID: | 154810 |
NCBI Accession: | NP_001287936.1 |
UniProt Secondary Accession: | Q8IY63,Q63HK7, Q8NDN0, Q8TEN8, Q8WXD1, Q96CM5, |
UniProt Related Accession: | Q8IY63 |
Molecular Weight: | 101,179 Da |
NCBI Full Name: | angiomotin-like protein 1 isoform 2 |
NCBI Synonym Full Names: | angiomotin like 1 |
NCBI Official Symbol: | AMOTL1 |
NCBI Official Synonym Symbols: | JEAP |
NCBI Protein Information: | angiomotin-like protein 1 |
UniProt Protein Name: | Angiomotin-like protein 1 |
Protein Family: | Angiomotin-like protein |
UniProt Gene Name: | AMOTL1 |