| UniProt Protein Function: | Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. |
| NCBI Summary: | The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q8IY63 |
| NCBI GenInfo Identifier: | 666335625 |
| NCBI Gene ID: | 154810 |
| NCBI Accession: | NP_001287936.1 |
| UniProt Secondary Accession: | Q8IY63,Q63HK7, Q8NDN0, Q8TEN8, Q8WXD1, Q96CM5, |
| UniProt Related Accession: | Q8IY63 |
| Molecular Weight: | 101,179 Da |
| NCBI Full Name: | angiomotin-like protein 1 isoform 2 |
| NCBI Synonym Full Names: | angiomotin like 1 |
| NCBI Official Symbol: | AMOTL1 |
| NCBI Official Synonym Symbols: | JEAP |
| NCBI Protein Information: | angiomotin-like protein 1 |
| UniProt Protein Name: | Angiomotin-like protein 1 |
| Protein Family: | Angiomotin-like protein |
| UniProt Gene Name: | AMOTL1 |
