Anti-AGTPBP1 Antibody (CAB13081)
- SKU:
- CAB13081
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-AGTPBP1 Antibody |
| 抗体コード: | CAB13081 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 320-520 of human AGTPBP1 (NP_056054.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, Jurkat, 293T, A-549, Mouse pancreas, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 320-520 of human AGTPBP1 (NP_056054.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PPEV DDVV DESD DNDD IDVE AENE TENE DDLD QNFK NDDI ETDI NKLK PQQE PGRT IEDL KMYE HLFP ELVD DFQD YDLI SKEP KPFV FEGK VRGP IVVP TAGE ETSG NSGN LRKV VMKE NISS KGDE GEKK STFM DLAK EDIK DNDR TLQQ QPGD QNRT ISSV HGLN NDIV KALD RITL QNIP SQTA PGFT AEMK KDCS L |
| 遺伝子ID: | 23287 |
| Uniprot: | Q9UPW5 |
| セルラーロケーション: | Cytoplasm, Mitochondrion, Nucleus, cytosol |
| 計算された分子量: | 133kDa/138kDa |
| 観察された分子量: | 138kDa |
| 同義語: | AGTPBP1, CCP1, NNA1 |
| バックグラウンド: |
| UniProt Protein Function: | Nna1: Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Interacts with MYLK. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.4.17.-; Protease Chromosomal Location of Human Ortholog: 9q21.33 Cellular Component: cytoplasm; cytosol; mitochondrion; nucleus Molecular Function:metallocarboxypeptidase activity; tubulin binding Biological Process: cerebellar Purkinje cell differentiation; eye photoreceptor cell differentiation; mitochondrion organization and biogenesis; neuromuscular process; olfactory bulb development |
| NCBI Summary: | NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.[supplied by OMIM, Jul 2002] |
| UniProt Code: | Q9UPW5 |
| NCBI GenInfo Identifier: | 160019039 |
| NCBI Gene ID: | 23287 |
| NCBI Accession: | Q9UPW5.3 |
| UniProt Secondary Accession: | Q9UPW5,Q5VV80, Q63HM7, Q658P5, Q6P9D6, Q9H8U6, Q9H9W8 Q9NVK1, B4DIT6, B4DRZ8, |
| UniProt Related Accession: | Q9UPW5 |
| Molecular Weight: | 138,647 Da |
| NCBI Full Name: | Cytosolic carboxypeptidase 1 |
| NCBI Synonym Full Names: | ATP/GTP binding protein 1 |
| NCBI Official Symbol: | AGTPBP1 |
| NCBI Official Synonym Symbols: | CCP1; NNA1 |
| NCBI Protein Information: | cytosolic carboxypeptidase 1 |
| UniProt Protein Name: | Cytosolic carboxypeptidase 1 |
| UniProt Synonym Protein Names: | ATP/GTP-binding protein 1; Nervous system nuclear protein induced by axotomy protein 1 homolog |
| UniProt Gene Name: | AGTPBP1 |
| UniProt Entry Name: | CBPC1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using AGTPBP1 antibody (CAB13081) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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