Anti-ADORA1 Antibody (RACO0366)
- SKU:
- RACO0366
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- ELISA
- Application:
- IHC
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 商品名: | ADORA1 Antibody |
| Product SKU: | RACO0366 |
| サイズ: | 50ul |
| 宿主種: | Homo sapiens (Human) |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | WB:1:500-1:5000, IHC:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | A synthesized peptide derived from human ADORA1 |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | Affinity-chromatography |
| 抗体のクローン性: | Monoclonal |
| アイソタイプ: | Rabbit IgG |
| Conjugate: | Non-conjugated |
| バックグラウンド: | Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. |
| シノニム: | Adenosine receptor A1, ADORA1 |
 | IHC image of RACO0366 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
 | Western Blot. Positive WB detected in A549 whole cell lysate 293 whole cell lysate U87 whole cell lysate All lanes ADORA1 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 37, 14 kDa. Observed band size: 37 kDa. |
| UniProt Protein Function: | ADORA1: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Endoplasmic reticulum; Receptor, GPCR; Apoptosis; GPCR, family 1 Chromosomal Location of Human Ortholog: 1q32.1 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:protein binding Biological Process: cell-cell signaling; inflammatory response; nervous system development; phagocytosis; signal transduction |
| NCBI Summary: | The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P30542 |
| NCBI GenInfo Identifier: | 231473 |
| NCBI Gene ID: | 134 |
| NCBI Accession: | P30542.1 |
| UniProt Secondary Accession: | P30542,Q6FHK3, Q8TAM8, A6NFY5, A6NGP4, A8K1L3, B3KXQ4 D2CGD0, |
| UniProt Related Accession: | P30542 |
| Molecular Weight: | 13,348 Da |
| NCBI Full Name: | Adenosine receptor A1 |
| NCBI Synonym Full Names: | adenosine A1 receptor |
| NCBI Official Symbol: | ADORA1 |
| NCBI Official Synonym Symbols: | RDC7 |
| NCBI Protein Information: | adenosine receptor A1 |
| UniProt Protein Name: | Adenosine receptor A1 |
| Protein Family: | Adenosine receptor |
| UniProt Gene Name: | ADORA1 |
| UniProt Entry Name: | AA1R_HUMAN |