Anti-ADGRB3 Antibody (CAB11956)
- SKU:
- CAB11956
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ADGRB3 Antibody |
| 抗体コード: | CAB11956 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-280 of human ADGRB3 (NP_001695.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-280 of human ADGRB3 (NP_001695.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | YLKF SKKD LSCS NFSL LAYQ FDHF SHEK IKDL LRKN HSIM QLCN SKNA FVFL QYDK NFIQ IRRV FPTN FPGL QKKG EEDQ KSFF EFLV LNKV SPSQ FGCH VLCT WLES CLKS ENGR TESC GIMY TKCT CPQH LGEW GIDD QSLI LLNN VVLP LNEQ TEGC LTQE LQTT QVCN LTRE AKRP PKEE FGMM GDHT IKSQ RPRS VHEK RVPQ EQA |
| 遺伝子ID: | 577 |
| Uniprot: | O60242 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 55kDa/171kDa |
| 観察された分子量: | 180kDa |
| 同義語: | ADGRB3, BAI3 |
| バックグラウンド: | This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. |
| UniProt Protein Function: | BAI3: May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. |
| UniProt Protein Details: | Protein type:GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 6q12-q13 Cellular Component: plasma membrane Molecular Function:GTPase activator activity; protein binding Biological Process: myoblast fusion; regulation of dendrite morphogenesis |
| NCBI Summary: | This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60242 |
| NCBI GenInfo Identifier: | 311033353 |
| NCBI Gene ID: | 577 |
| NCBI Accession: | O60242.2 |
| UniProt Secondary Accession: | O60242,O60297, Q2NKN6, Q5VY37, Q9BX54, B7Z1K0, |
| UniProt Related Accession: | O60242 |
| Molecular Weight: | 172kDa |
| NCBI Full Name: | Adhesion G protein-coupled receptor B3 |
| NCBI Synonym Full Names: | adhesion G protein-coupled receptor B3 |
| NCBI Official Symbol: | ADGRB3 |
| NCBI Official Synonym Symbols: | BAI3 |
| NCBI Protein Information: | adhesion G protein-coupled receptor B3 |
| UniProt Protein Name: | Adhesion G protein-coupled receptor B3 |
| UniProt Synonym Protein Names: | Brain-specific angiogenesis inhibitor 3 |
| Protein Family: | Adhesion G protein-coupled receptor |
| UniProt Gene Name: | ADGRB3 |
 | Western blot analysis of extracts of 293T cells, using ADGRB3 antibody (CAB11956) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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