ZBTB7B Antibody (PACO13293)
- SKU:
- PACO13293
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ZBTB7B Antibody (PACO13293) |
抗体コード: | PACO13293 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human ZBTB7B |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | zinc finger and BTB domain containing 7B;ZBTB7B;DKFZp686G01254;THPOK;ZBTB15;ZFP67;ZNF857B;c-Krox;hcKrox ; |
UniProt Protein Function: | ZBTB7B: Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes. |
UniProt Protein Details: | Protein type:C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: nucleoplasm; nucleus Molecular Function:DNA binding; metal ion binding Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; multicellular organismal development; ectoderm development; cell differentiation |
NCBI Summary: | This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |
UniProt Code: | O15156 |
NCBI GenInfo Identifier: | 51316943 |
NCBI Gene ID: | 51043 |
NCBI Accession: | O15156.2 |
UniProt Secondary Accession: | O15156,Q68DR2, Q96EP2, B4E3K5, D3DV83, J3KQQ3, |
UniProt Related Accession: | O15156 |
Molecular Weight: | 539 |
NCBI Full Name: | Zinc finger and BTB domain-containing protein 7B |
NCBI Synonym Full Names: | zinc finger and BTB domain containing 7B |
NCBI Official Symbol: | ZBTB7B |
NCBI Official Synonym Symbols: | CKROX; THPOK; ZFP67; ZBTB15; ZFP-67; c-KROX; hcKROX; ZNF857B |
NCBI Protein Information: | zinc finger and BTB domain-containing protein 7B; zinc finger protein 857B; zinc finger protein Th-POK; zinc finger protein 67 homolog; zinc finger and BTB domain containing 15; T-helper-inducing POZ/Krueppel-like factor; krueppel-related zinc finger protein cKrox |
UniProt Protein Name: | Zinc finger and BTB domain-containing protein 7B |
UniProt Synonym Protein Names: | Krueppel-related zinc finger protein cKrox; hcKrox; T-helper-inducing POZ/Krueppel-like factor; Zinc finger and BTB domain-containing protein 15; Zinc finger protein 67 homolog; Zfp-67; Zinc finger protein 857B; Zinc finger protein Th-POK |
Protein Family: | Zinc finger and BTB domain-containing protein |
UniProt Gene Name: | ZBTB7B |
UniProt Entry Name: | ZBT7B_HUMAN |