YY1AP1 Antibody (PACO61462)
- SKU:
- PACO61462
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | YY1AP1 Antibody (PACO61462) |
抗体コード: | PACO61462 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human YY1-associated protein 1 protein (335-466AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO61462 diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | Western Blot. Positive WB detected in: SH-SY5Y whole cell lysate, Hela whole cell lysate, K562 whole cell lysate, Jurkat whole cell lysate, HL60 whole cell lysate, 293 whole cell lysate. All lanes: YY1AP1 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 88, 84, 82, 81, 76, 80, 51, 96, 98 kDa. Observed band size: 88 kDa. |
![]() | Immunofluorescence staining of HepG2 cells with PACO61462 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication. Enhances transcription activation by YY1. Plays a role in cell cycle regulation. |
シノニム: | YY1-associated protein 1, Hepatocellular carcinoma susceptibility protein1, YY1AP1 |
UniProt Protein Function: | YY1AP1: Enhances transcription activation by YY1. May play a role in cell cycle regulation. 7 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 1q22 Cellular Component: nucleus Molecular Function:protein binding Biological Process: regulation of cell cycle |
NCBI Summary: | The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9H869 |
NCBI GenInfo Identifier: | 147744601 |
NCBI Gene ID: | 55249 |
NCBI Accession: | Q9H869.2 |
UniProt Secondary Accession: | Q9H869,Q5VYZ1, Q5VYZ4, Q5VYZ7, Q7L4C3, Q7L5E2, B0QZ54 B4DMP2, B4E0I0, D3DV96, D3DV98, H7BY62, |
UniProt Related Accession: | Q9H869 |
Molecular Weight: | 97,716 Da |
NCBI Full Name: | YY1-associated protein 1 |
NCBI Synonym Full Names: | YY1 associated protein 1 |
NCBI Official Symbol: | YY1AP1 |
NCBI Official Synonym Symbols: | YAP; HCCA1; HCCA2; YY1AP |
NCBI Protein Information: | YY1-associated protein 1 |
UniProt Protein Name: | YY1-associated protein 1 |
UniProt Synonym Protein Names: | Hepatocellular carcinoma susceptibility protein; Hepatocellular carcinoma-associated protein 2 |
Protein Family: | YY1-associated protein |
UniProt Gene Name: | YY1AP1 |
UniProt Entry Name: | YYAP1_HUMAN |
Antibodies |
Anti-YY1AP1 Antibody (CAB13104) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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