WDYHV1 Antibody, HRP conjugated (PACO39595)
- SKU:
- PACO39595
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | WDYHV1 Antibody, HRP conjugated (PACO39595) |
抗体コード: | PACO39595 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Protein N-terminal glutamine amidohydrolase protein (1-205AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine (By similarity). |
シノニム: | Protein N-terminal glutamine amidohydrolase (EC 3.5.1.122) (Protein NH2-terminal glutamine deamidase) (N-terminal Gln amidase) (Nt(Q)-amidase) (WDYHV motif-containing protein 1), WDYHV1, C8orf32 NTAQ1 |
UniProt Protein Function: | WDYHV1: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N- terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C- terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine. Belongs to the NTAQ1 family.Protein type: EC 3.5.1.-Chromosomal Location of Human Ortholog: 8q24.13Cellular Component: cytosol; nucleusMolecular Function: protein bindingBiological Process: protein modification process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q96HA8 |
NCBI GenInfo Identifier: | 152112225 |
NCBI Gene ID: | 55093 |
NCBI Accession: | Q96HA8.2 |
UniProt Secondary Accession: | Q96HA8,Q9NW95, B4DE68 |
UniProt Related Accession: | Q96HA8 |
Molecular Weight: | 16,736 Da |
NCBI Full Name: | Protein N-terminal glutamine amidohydrolase |
NCBI Synonym Full Names: | WDYHV motif containing 1 |
NCBI Official Symbol: | WDYHV1 |
NCBI Official Synonym Symbols: | C8orf32 |
NCBI Protein Information: | protein N-terminal glutamine amidohydrolase |
UniProt Protein Name: | Protein N-terminal glutamine amidohydrolase |
UniProt Synonym Protein Names: | Protein NH2-terminal glutamine deamidase; N-terminal Gln amidase; Nt(Q)-amidase; WDYHV motif-containing protein 1 |
Protein Family: | |
UniProt Gene Name: | WDYHV1 |
UniProt Entry Name: | NTAQ1_HUMAN |