WDR35 Antibody, HRP conjugated (PACO62820)
- SKU:
- PACO62820
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | WDR35 Antibody, HRP conjugated (PACO62820) |
抗体コード: | PACO62820 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human WD repeat-containing protein 35 protein (954-1181AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Required for ciliogenesis. May promote CASP3 activation and TNF-stimulated apoptosis. |
シノニム: | WD repeat-containing protein 35 (Intraflagellar transport protein 121 homolog), WDR35, IFT121 KIAA1336 |
UniProt Protein Function: | WDR35: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Two alternatively spliced human isoforms have been described. |
UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 2p24.1 Cellular Component: axoneme; centrosome; cilium Molecular Function:phosphoinositide binding Disease: Cranioectodermal Dysplasia 2; Short-rib Thoracic Dysplasia 7 With Or Without Polydactyly |
NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.[provided by RefSeq, Sep 2010] |
UniProt Code: | Q9P2L0 |
NCBI GenInfo Identifier: | 48474987 |
NCBI Gene ID: | 57539 |
NCBI Accession: | Q9P2L0.3 |
UniProt Secondary Accession: | Q9P2L0,Q4ZG01, Q8NE11, B3KVI5, |
UniProt Related Accession: | Q9P2L0 |
Molecular Weight: | 134kDa |
NCBI Full Name: | WD repeat-containing protein 35 |
NCBI Synonym Full Names: | WD repeat domain 35 |
NCBI Official Symbol: | WDR35 |
NCBI Official Synonym Symbols: | CED2; IFTA1; SRTD7; IFT121 |
NCBI Protein Information: | WD repeat-containing protein 35 |
UniProt Protein Name: | WD repeat-containing protein 35 |
UniProt Synonym Protein Names: | Intraflagellar transport protein 121 homolog |
Protein Family: | WD repeat-containing protein |
UniProt Gene Name: | WDR35 |