WDFY1 Antibody, Biotin conjugated (PACO49237)
- SKU:
- PACO49237
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | WDFY1 Antibody, Biotin conjugated (PACO49237) |
抗体コード: | PACO49237 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human WD repeat and FYVE domain-containing protein 1 protein (261-357AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-β and inflammatory cytokines. |
シノニム: | WD repeat and FYVE domain-containing protein 1 (FENS-1) (Phosphoinositide-binding protein 1) (WD40- and FYVE domain-containing protein 1) (Zinc finger FYVE domain-containing protein 17), WDFY1, KIAA1435 WDF1 ZFYVE17 |
UniProt Protein Function: | WDFY1: Binds PtdIns3P in vitro with high specificity over other phosphoinositides.Chromosomal Location of Human Ortholog: 2q36.1Cellular Component: cytosol; early endosome; nucleusMolecular Function: phosphatidylinositol binding; protein bindingBiological Process: positive regulation of toll-like receptor 3 signaling pathway; positive regulation of toll-like receptor 4 signaling pathway |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is a phosphatidylinositol 3-phosphate binding protein, which contains a FYVE zinc finger domain and multiple WD-40 repeat domains. When exogenously expressed, it localizes to early endosomes. Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain. [provided by RefSeq, Jan 2015] |
UniProt Code: | Q8IWB7 |
NCBI GenInfo Identifier: | 18482373 |
NCBI Gene ID: | 57590 |
NCBI Accession: | NP_065881.1 |
UniProt Secondary Accession: | Q8IWB7,Q53S17, Q9H9D5, Q9P2B3 |
UniProt Related Accession: | Q8IWB7 |
Molecular Weight: | |
NCBI Full Name: | WD repeat and FYVE domain-containing protein 1 |
NCBI Synonym Full Names: | WD repeat and FYVE domain containing 1 |
NCBI Official Symbol: | WDFY1 |
NCBI Official Synonym Symbols: | WDF1; FENS-1; ZFYVE17 |
NCBI Protein Information: | WD repeat and FYVE domain-containing protein 1 |
UniProt Protein Name: | WD repeat and FYVE domain-containing protein 1 |
UniProt Synonym Protein Names: | FENS-1; Phosphoinositide-binding protein 1; WD40- and FYVE domain-containing protein 1; Zinc finger FYVE domain-containing protein 17 |
Protein Family: | WD repeat and FYVE domain-containing protein |
UniProt Gene Name: | WDFY1 |
UniProt Entry Name: | WDFY1_HUMAN |