VPS54 Antibody (PACO04541)
- SKU:
- PACO04541
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | VPS54 Antibody |
抗体コード: | PACO04541 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | IHC:1:100-1:300 |
反応性: | Human |
免疫原: | synthesized peptide derived from the Internal region of human VPS54. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | VPS54; HCC8; Vacuolar protein sorting-associated protein 54; Hepatocellular carcinoma protein 8; Tumor antigen HOM-HCC-8; Tumor antigen SLP-8p |
UniProt Protein Function: | Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:18367545). Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling (PubMed:25799061). |
NCBI Summary: | This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9P1Q0 |
NCBI GenInfo Identifier: | 82583721 |
NCBI Gene ID: | 51542 |
NCBI Accession: | Q9P1Q0.2 |
UniProt Secondary Accession: | Q9P1Q0,Q5VIR5, Q86YF7, Q8N6G3, Q9NPV0, Q9NT07, Q9NUJ0 |
UniProt Related Accession: | Q9P1Q0 |
Molecular Weight: | 15,982 Da |
NCBI Full Name: | Vacuolar protein sorting-associated protein 54 |
NCBI Synonym Full Names: | VPS54, GARP complex subunit |
NCBI Official Symbol: | VPS54 |
NCBI Official Synonym Symbols: | WR; HCC8; SLP-8p; VPS54L; hVps54L; PPP1R164 |
NCBI Protein Information: | vacuolar protein sorting-associated protein 54 |
UniProt Protein Name: | Vacuolar protein sorting-associated protein 54 |
UniProt Synonym Protein Names: | Hepatocellular carcinoma protein 8; Tumor antigen HOM-HCC-8; Tumor antigen SLP-8p |
UniProt Gene Name: | VPS54 |
UniProt Entry Name: | VPS54_HUMAN |