VPS25 Antibody, HRP conjugated (PACO42087)
- SKU:
- PACO42087
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | VPS25 Antibody, HRP conjugated (PACO42087) |
抗体コード: | PACO42087 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Vacuolar protein-sorting-associated protein 25 protein (1-176AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses. |
シノニム: | Vacuolar protein-sorting-associated protein 25 (hVps25) (Dermal papilla-derived protein 9) (ELL-associated protein of 20 kDa) (ESCRT-II complex subunit VPS25), VPS25, DERP9 EAP20 |
UniProt Protein Function: | VPS25: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses. Belongs to the VPS25 family. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 17q21.31 Cellular Component: nucleoplasm; mitochondrion; nucleolus; endosome membrane; nucleus; cytosol Molecular Function:protein binding; protein homodimerization activity; structural molecule activity Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; protein targeting to vacuole during ubiquitin-dependent protein catabolic process via the MVB pathway; endosome transport |
NCBI Summary: | This gene encodes a protein that is a subunit of the endosomal sorting complex required for transport II (ESCRT-II). This protein complex functions in sorting of ubiquitinated membrane proteins during endocytosis. A pseudogene of this gene is present on chromosome 1. [provided by RefSeq, Jul 2013] |
UniProt Code: | Q9BRG1 |
NCBI GenInfo Identifier: | 73920459 |
NCBI Gene ID: | 84313 |
NCBI Accession: | Q9BRG1.1 |
UniProt Related Accession: | Q9BRG1 |
Molecular Weight: | 20kDa |
NCBI Full Name: | Vacuolar protein-sorting-associated protein 25 |
NCBI Synonym Full Names: | vacuolar protein sorting 25 homolog |
NCBI Official Symbol: | VPS25 |
NCBI Official Synonym Symbols: | DERP9; EAP20; FAP20 |
NCBI Protein Information: | vacuolar protein-sorting-associated protein 25 |
UniProt Protein Name: | Vacuolar protein-sorting-associated protein 25 |
UniProt Synonym Protein Names: | Dermal papilla-derived protein 9; ELL-associated protein of 20 kDa; ESCRT-II complex subunit VPS25 |
Protein Family: | Vacuolar protein sorting-associated protein |
UniProt Gene Name: | VPS25 |
UniProt Entry Name: | VPS25_HUMAN |