VPS18 Antibody, Biotin conjugated (PACO62826)
- SKU:
- PACO62826
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | VPS18 Antibody, Biotin conjugated (PACO62826) |
抗体コード: | PACO62826 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Vacuolar protein sorting-associated protein 18 homolog protein (298-515AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for fusion of endosomes and autophagosomes with lysosomes. Involved in dendrite development of Pukinje cells (By similarity). |
シノニム: | Vacuolar protein sorting-associated protein 18 homolog (hVPS18), VPS18, KIAA1475 |
UniProt Code: | Q9P253 |
NCBI GenInfo Identifier: | 17978485 |
NCBI Gene ID: | |
NCBI Accession: | NP_065908 |
Molecular Weight: | |
NCBI Full Name: | vacuolar protein sorting-associated protein 18 homolog |
UniProt Protein Name: | Vacuolar protein sorting-associated protein 18 homolog |
Protein Family: | Vacuolar protein sorting-associated protein |
UniProt Gene Name: | VPS18 |
UniProt Entry Name: | VPS18_HUMAN |