UXS1 Antibody (PACO38310)
- SKU:
- PACO38310
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | UXS1 Antibody (PACO38310) |
抗体コード: | PACO38310 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human UDP-glucuronic acid, decarboxylase 1 protein (201-420AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: UXS1 antibody at 6µg/ml. Lane 1: Mouse lung tissue. Lane 2: Jurkat whole cell lysate. Lane 3: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 48, 49, 29 kDa. Observed band size: 48 kDa. |
バックグラウンド: | Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid, to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis. |
シノニム: | UDP-glucuronic acid, decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1), UXS1 |
UniProt Protein Function: | UXS1: Catalyzes the NAD-dependent decarboxylation of UDP- glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis. Belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 4.1.1.35; LyaseChromosomal Location of Human Ortholog: 2q12.2Molecular Function: protein homodimerization activity; UDP-glucuronate decarboxylase activityBiological Process: protein tetramerization |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes an enzyme found in the perinuclear Golgi which catalyzes the synthesis of UDP-xylose used in glycosaminoglycan (GAG) synthesis on proteoglycans. The GAG chains are covalently attached to proteoglycans which participate in signaling pathways during development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014] |
UniProt Code: | Q8NBZ7 |
NCBI GenInfo Identifier: | 74730150 |
NCBI Gene ID: | 80146 |
NCBI Accession: | Q8NBZ7.1 |
UniProt Secondary Accession: | Q8NBZ7,Q8NBX3, Q9H5C2 |
UniProt Related Accession: | Q8NBZ7 |
Molecular Weight: | 28,275 Da |
NCBI Full Name: | UDP-glucuronic acid decarboxylase 1 |
NCBI Synonym Full Names: | UDP-glucuronate decarboxylase 1 |
NCBI Official Symbol: | UXS1 |
NCBI Official Synonym Symbols: | UGD; SDR6E1 |
NCBI Protein Information: | UDP-glucuronic acid decarboxylase 1 |
UniProt Protein Name: | UDP-glucuronic acid decarboxylase 1 |
UniProt Synonym Protein Names: | UDP-glucuronate decarboxylase 1; UGD; UXS-1 |
Protein Family: | UDP-glucuronic acid decarboxylase |
UniProt Gene Name: | UXS1 |
UniProt Entry Name: | UXS1_HUMAN |