USB1 Antibody, HRP conjugated (PACO59010)
- SKU:
- PACO59010
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | USB1 Antibody, HRP conjugated (PACO59010) |
抗体コード: | PACO59010 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human U6 snRNA phosphodiesterase protein (1-90AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate. |
シノニム: | U6 snRNA phosphodiesterase (hUsb1) (EC 3.1.4), USB1, C16orf57 |
UniProt Protein Function: | Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate. |
NCBI Summary: | This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011] |
UniProt Code: | Q9BQ65 |
NCBI GenInfo Identifier: | 306035177 |
NCBI Gene ID: | 79650 |
NCBI Accession: | NP_001182231.1 |
UniProt Secondary Accession: | Q9BQ65,Q96FZ9, Q9H8X8, B4DWE3, B4DZW5, |
UniProt Related Accession: | Q9BQ65 |
Molecular Weight: | 20,802 Da |
NCBI Full Name: | U6 snRNA phosphodiesterase isoform 2 |
NCBI Synonym Full Names: | U6 snRNA biogenesis phosphodiesterase 1 |
NCBI Official Symbol: | USB1 |
NCBI Official Synonym Symbols: | PN; Mpn1; HVSL1; hUsb1; C16orf57 |
NCBI Protein Information: | U6 snRNA phosphodiesterase |
UniProt Protein Name: | U6 snRNA phosphodiesterase |
Protein Family: | U6 snRNA phosphodiesterase |
UniProt Gene Name: | USB1 |