UGT2B4 Antibody, HRP conjugated (PACO30993)
- SKU:
- PACO30993
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Description
抗体名: | UGT2B4 Antibody, HRP conjugated (PACO30993) |
抗体コード: | PACO30993 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human UDP-glucuronosyltransferase 2B4 protein (281-481AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid, |
シノニム: | UDP-glucuronosyltransferase 2B4 (UDPGT 2B4) (EC 2.4.1.17) (HLUG25) (Hyodeoxycholic acid, specific UDPGT) (UDPGTh-1), UGT2B4, UGT2B11 |
UniProt Protein Function: | UGT2B4: UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4- nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid. Belongs to the UDP-glycosyltransferase family. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - pentose and glucuronate interconversions; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - retinol; Carbohydrate Metabolism - ascorbate and aldarate; Membrane protein, integral; Xenobiotic Metabolism - drug metabolism - other enzymes; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Carbohydrate Metabolism - starch and sucrose; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.4.1.17; Lipid Metabolism - androgen and estrogen Chromosomal Location of Human Ortholog: 4q13.3 Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; integral to membrane Molecular Function:retinoic acid binding; glucuronosyltransferase activity Biological Process: flavonoid biosynthetic process; metabolic process; xenobiotic metabolic process; estrogen catabolic process; cellular response to hormone stimulus |
UniProt Code: | P06133 |
NCBI GenInfo Identifier: | 6175083 |
NCBI Gene ID: | 7363 |
NCBI Accession: | P06133.2 |
UniProt Secondary Accession: | P06133,O60731, O60867, O75614, P36538, Q1HBF9, Q6QQX7 A6NCP7, B4DT75, G5E9X8, |
UniProt Related Accession: | P06133 |
Molecular Weight: | Observed MW: 50kDaCalculated MW: 42kDa/44kDa/60kDa |
NCBI Full Name: | UDP-glucuronosyltransferase 2B4 |
NCBI Synonym Full Names: | UDP glucuronosyltransferase 2 family, polypeptide B4 |
NCBI Official Symbol: | UGT2B4 |
NCBI Official Synonym Symbols: | HLUG25; UDPGTH1; UGT2B11; UDPGT2B4; UDPGTh-1 |
NCBI Protein Information: | UDP-glucuronosyltransferase 2B4; UDPGT 2B4; hyodeoxycholic acid; hyodeoxycholic acid-specific UDPGT; UDP-glucuronyltransferase, family 2, beta-4 |
UniProt Protein Name: | UDP-glucuronosyltransferase 2B4 |
UniProt Synonym Protein Names: | HLUG25; Hyodeoxycholic acid-specific UDPGT; UDPGTh-1 |
Protein Family: | UDP-glucuronosyltransferase |
UniProt Gene Name: | UGT2B4 |
UniProt Entry Name: | UD2B4_HUMAN |