UBE2E3 Antibody (PACO53510)
- SKU:
- PACO53510
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | UBE2E3 Antibody (PACO53510) |
抗体コード: | PACO53510 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Ubiquitin-conjugating enzyme E2 E3 protein (2-128AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescent analysis of A549 cells using PACO53510 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. |
シノニム: | Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3), UBE2E3, UBCE4 UBCH9 |
UniProt Protein Function: | UBE2E3: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. Belongs to the ubiquitin-conjugating enzyme family. |
UniProt Protein Details: | Protein type:EC 6.3.2.19; Ubiquitin ligase; Ubiquitin conjugating system; Ligase Chromosomal Location of Human Ortholog: 2q32.1 Molecular Function:protein binding; ubiquitin-protein ligase activity |
NCBI Summary: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013] |
UniProt Code: | Q969T4 |
NCBI GenInfo Identifier: | 47606197 |
NCBI Gene ID: | 10477 |
NCBI Accession: | Q969T4.1 |
UniProt Secondary Accession: | Q969T4,Q5U0R7, Q7Z4W4, B2RAD6, D3DPG3, |
UniProt Related Accession: | Q969T4 |
Molecular Weight: | 22,913 Da |
NCBI Full Name: | Ubiquitin-conjugating enzyme E2 E3 |
NCBI Synonym Full Names: | ubiquitin conjugating enzyme E2 E3 |
NCBI Official Symbol: | UBE2E3 |
NCBI Official Synonym Symbols: | UBCH9; UbcM2 |
NCBI Protein Information: | ubiquitin-conjugating enzyme E2 E3 |
UniProt Protein Name: | Ubiquitin-conjugating enzyme E2 E3 |
UniProt Synonym Protein Names: | E2 ubiquitin-conjugating enzyme E3; UbcH9; Ubiquitin carrier protein E3; Ubiquitin-conjugating enzyme E2-23 kDa; Ubiquitin-protein ligase E3 |
Protein Family: | Ubiquitin-conjugating enzyme |
UniProt Gene Name: | UBE2E3 |
UniProt Entry Name: | UB2E3_HUMAN |