TRMT5 Antibody (PACO12933)
- SKU:
- PACO12933
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TRMT5 Antibody (PACO12933) |
抗体コード: | PACO12933 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human TRMT5 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae);TRMT5;KIAA1393;MGC111453;TRM5 ; |
UniProt Protein Function: | TRMT5: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. Belongs to the TRM5 / TYW2 family.Protein type: EC 2.1.1.228; MethyltransferaseChromosomal Location of Human Ortholog: 14q23.1Cellular Component: mitochondrial matrix; nucleusBiological Process: tRNA methylationDisease: Combined Oxidative Phosphorylation Deficiency 26 |
UniProt Protein Details: | |
NCBI Summary: | tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q32P41 |
NCBI GenInfo Identifier: | 145275187 |
NCBI Gene ID: | 57570 |
NCBI Accession: | NP_065861.2 |
UniProt Secondary Accession: | Q32P41 |
UniProt Related Accession: | Q32P41 |
Molecular Weight: | 55 kDa |
NCBI Full Name: | tRNA (guanine(37)-N1)-methyltransferase |
NCBI Synonym Full Names: | tRNA methyltransferase 5 |
NCBI Official Symbol: | TRMT5 |
NCBI Official Synonym Symbols: | TRM5; COXPD26; KIAA1393 |
NCBI Protein Information: | tRNA (guanine(37)-N1)-methyltransferase |
UniProt Protein Name: | tRNA (guanine(37)-N1)-methyltransferase |
UniProt Synonym Protein Names: | M1G-methyltransferase |
Protein Family: | |
UniProt Gene Name: | TRMT5 |
UniProt Entry Name: | TRM5_HUMAN |