TRIM38 Antibody (PACO30814)
- SKU:
- PACO30814
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TRIM38 Antibody (PACO30814) |
抗体コード: | PACO30814 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
反応性: | Human |
免疫原: | Recombinant Human E3 ubiquitin-protein ligase TRIM38 protein (45-259AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: TRIM38 antibody at 4µg/ml + Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 54 kDa Observed band size: 54 kDa . |
バックグラウンド: | E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling. |
シノニム: | E3 ubiquitin-protein ligase TRIM38 (EC 2.3.2.27) (RING finger protein 15) (RING-type E3 ubiquitin transferase TRIM38) (Tripartite motif-containing protein 38) (Zinc finger protein RoRet), TRIM38, RNF15 RORET |
UniProt Protein Function: | TRIM38: E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling. {ECO:0000269|PubMed:23056470} |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: cytosol Molecular Function:protein binding; signal transducer activity Biological Process: activation of NF-kappaB transcription factor; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity; positive regulation of virion penetration into host cell |
NCBI Summary: | This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012] |
UniProt Code: | O00635 |
NCBI GenInfo Identifier: | 21362879 |
NCBI Gene ID: | 10475 |
NCBI Accession: | O00635.1 |
UniProt Secondary Accession: | O00635,B2R862, |
UniProt Related Accession: | O00635 |
Molecular Weight: | 53,416 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase TRIM38 |
NCBI Synonym Full Names: | tripartite motif containing 38 |
NCBI Official Symbol: | TRIM38 |
NCBI Official Synonym Symbols: | RNF15; RORET |
NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM38 |
UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM38 |
UniProt Synonym Protein Names: | RING finger protein 15; Tripartite motif-containing protein 38; Zinc finger protein RoRet |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | TRIM38 |
UniProt Entry Name: | TRI38_HUMAN |
Antibodies | ELISA Kits |
Anti-TRIM38 Antibody (CAB2600) | TRIM38 Colorimetric Cell-Based ELISA |
TRIM38 Antibody (PACO02323) | |
TRIM38 Antibody (PACO12916) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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