TRIM38 Antibody (PACO02323)
- SKU:
- PACO02323
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TRIM38 Antibody |
抗体コード: | PACO02323 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human, Mouse |
免疫原: | synthesized peptide derived from the Internal region of human RNF15. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | TRIM38; RNF15; RORET; Tripartite motif-containing protein 38; RING finger protein 15; Zinc finger protein RoRet |
UniProt Protein Function: | TRIM38: E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling. {ECO:0000269|PubMed:23056470} |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: cytosol Molecular Function:protein binding; signal transducer activity Biological Process: activation of NF-kappaB transcription factor; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity; positive regulation of virion penetration into host cell |
NCBI Summary: | This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012] |
UniProt Code: | O00635 |
NCBI GenInfo Identifier: | 21362879 |
NCBI Gene ID: | 10475 |
NCBI Accession: | O00635.1 |
UniProt Secondary Accession: | O00635,B2R862, |
UniProt Related Accession: | O00635 |
Molecular Weight: | 53,416 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase TRIM38 |
NCBI Synonym Full Names: | tripartite motif containing 38 |
NCBI Official Symbol: | TRIM38 |
NCBI Official Synonym Symbols: | RNF15; RORET |
NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM38 |
UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM38 |
UniProt Synonym Protein Names: | RING finger protein 15; Tripartite motif-containing protein 38; Zinc finger protein RoRet |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | TRIM38 |
UniProt Entry Name: | TRI38_HUMAN |