TREM1 Antibody (PACO01847)
- SKU:
- PACO01847
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 抗体名: | TREM1 Antibody |
| 抗体コード: | PACO01847 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | WB:1:500-1:2000 |
| 反応性: | Human |
| 免疫原: | synthesized peptide derived from the Internal region of human TREM-1. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | TREM1; Triggering receptor expressed on myeloid cells 1; TREM-1; Triggering receptor expressed on monocytes 1; CD354 |
| UniProt Protein Function: | TREM1: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 6p21.1 Cellular Component: integral to membrane; extracellular region; plasma membrane Molecular Function:receptor activity Biological Process: neutrophil chemotaxis; innate immune response; cytokine secretion during immune response; blood coagulation; leukocyte migration; chemokine metabolic process; humoral immune response |
| NCBI Summary: | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] |
| UniProt Code: | Q9NP99 |
| NCBI GenInfo Identifier: | 50401685 |
| NCBI Gene ID: | 54210 |
| NCBI Accession: | Q9NP99.1 |
| UniProt Secondary Accession: | Q9NP99,Q53FL8, Q5T2C9, Q86YU1, B4DWG2, K7EJW1, |
| UniProt Related Accession: | Q9NP99 |
| Molecular Weight: | 234 |
| NCBI Full Name: | Triggering receptor expressed on myeloid cells 1 |
| NCBI Synonym Full Names: | triggering receptor expressed on myeloid cells 1 |
| NCBI Official Symbol: | TREM1 |
| NCBI Official Synonym Symbols: | CD354; TREM-1 |
| NCBI Protein Information: | triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1 |
| UniProt Protein Name: | Triggering receptor expressed on myeloid cells 1 |
| UniProt Synonym Protein Names: | Triggering receptor expressed on monocytes 1; CD_antigen: CD354 |
| Protein Family: | Triggering receptor expressed on myeloid cells |
| UniProt Gene Name: | TREM1 |
| UniProt Entry Name: | TREM1_HUMAN |