TRDMT1 Antibody, Biotin conjugated (PACO55949)
- SKU:
- PACO55949
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | TRDMT1 Antibody, Biotin conjugated (PACO55949) |
抗体コード: | PACO55949 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human tRNA (cytosine(38)-C(5))-methyltransferase protein (170-269AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp). |
シノニム: | tRNA (cytosine(38)-C(5))-methyltransferase (EC 2.1.1.204) (DNA (cytosine-5)-methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet), TRDMT1, DNMT2 |
UniProt Protein Function: | TRDMT1: Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp). Belongs to the C5-methyltransferase family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - cysteine and methionine; EC 2.1.1.204; Methyltransferase; Methyltransferase, tRNA Chromosomal Location of Human Ortholog: 10p13 Cellular Component: cytoplasm; nucleoplasm Molecular Function:tRNA (cytosine-5-)-methyltransferase activity; tRNA methyltransferase activity Biological Process: tRNA methylation; tRNA modification |
NCBI Summary: | This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010] |
UniProt Code: | O14717 |
NCBI GenInfo Identifier: | 17374834 |
NCBI Gene ID: | 1787 |
NCBI Accession: | O14717.1 |
UniProt Secondary Accession: | O14717,O43669, Q86WW6, B0YJ02, B0YJ03, B0YJ07, B0YJ08 |
UniProt Related Accession: | O14717 |
Molecular Weight: | 45kDa |
NCBI Full Name: | tRNA (cytosine(38)-C(5))-methyltransferase |
NCBI Synonym Full Names: | tRNA aspartic acid methyltransferase 1 |
NCBI Official Symbol: | TRDMT1 |
NCBI Official Synonym Symbols: | DMNT2; DNMT2; PUMET; RNMT1; MHSAIIP |
NCBI Protein Information: | tRNA (cytosine(38)-C(5))-methyltransferase |
UniProt Protein Name: | tRNA (cytosine(38)-C(5))-methyltransferase |
UniProt Synonym Protein Names: | DNA (cytosine-5)-methyltransferase-like protein 2; Dnmt2; DNA methyltransferase homolog HsaIIP; DNA MTase homolog HsaIIP; M.HsaIIP; PuMet |
Protein Family: | tRNA |
UniProt Gene Name: | TRDMT1 |