TRAFD1 Antibody (PACO30782)
- SKU:
- PACO30782
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TRAFD1 Antibody (PACO30782) |
抗体コード: | PACO30782 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human TRAF-type zinc finger domain-containing protein 1 protein (2-300AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
バックグラウンド: | Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3. |
シノニム: | TRAF-type zinc finger domain-containing protein 1 (Protein FLN29), TRAFD1, FLN29 |
UniProt Protein Function: | FLN29: a protein of unknown function. Contains a C2H2 zinc finger frequently associated with DNA binding. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 12q Molecular Function:protein binding; metal ion binding Biological Process: negative regulation of innate immune response; response to cytokine stimulus |
NCBI Summary: | The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).[supplied by OMIM, Dec 2009] |
UniProt Code: | O14545 |
NCBI GenInfo Identifier: | 74754309 |
NCBI Gene ID: | 10906 |
NCBI Accession: | O14545.1 |
UniProt Secondary Accession: | O14545,A8K5L6, B4DI89, |
UniProt Related Accession: | O14545 |
Molecular Weight: | 19,034 Da |
NCBI Full Name: | TRAF-type zinc finger domain-containing protein 1 |
NCBI Synonym Full Names: | TRAF-type zinc finger domain containing 1 |
NCBI Official Symbol: | TRAFD1 |
NCBI Official Synonym Symbols: | FLN29 |
NCBI Protein Information: | TRAF-type zinc finger domain-containing protein 1; FLN29 gene product |
UniProt Protein Name: | TRAF-type zinc finger domain-containing protein 1 |
UniProt Synonym Protein Names: | Protein FLN29 |
Protein Family: | TRAF-type zinc finger domain-containing protein |
UniProt Gene Name: | TRAFD1 |
UniProt Entry Name: | TRAD1_HUMAN |