TNPO3 Antibody (PACO52474)
- SKU:
- PACO52474
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TNPO3 Antibody (PACO52474) |
抗体コード: | PACO52474 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Transportin-3 protein (382-458AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescent analysis of HepG2 cells using PACO52474 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins RBM4, SFRS1 and SFRS2, by recognizing phosphorylated RS domains. |
シノニム: | Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR), TNPO3, IPO12 |
UniProt Protein Function: | IPO3: Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins RBM4, SFRS1 and SFRS2, by recognizing phosphorylated RS domains. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Nuclear export; Karyopherin; Receptor, misc.; Nuclear importChromosomal Location of Human Ortholog: 7q32.1Cellular Component: intracellular membrane-bound organelle; cytoplasm; nucleusMolecular Function: protein binding; receptor activityBiological Process: splicing factor protein import into nucleusDisease: Muscular Dystrophy, Limb-girdle, Type 1f |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010] |
UniProt Code: | Q9Y5L0 |
NCBI GenInfo Identifier: | 300794233 |
NCBI Gene ID: | 23534 |
NCBI Accession: | NP_036602.1 |
UniProt Secondary Accession: | Q9Y5L0,Q6NUM1, Q96G71, Q96GU9, Q9Y3R2, A4D1K9, C9IZM0 |
UniProt Related Accession: | Q9Y5L0 |
Molecular Weight: | |
NCBI Full Name: | Homo sapiens transportin 3 (TNPO3), transcript variant 1, mRNA |
NCBI Synonym Full Names: | transportin 3 |
NCBI Official Symbol: | TNPO3 |
NCBI Official Synonym Symbols: | IPO12; TRNSR; LGMD1F; MTR10A; TRN-SR; TRN-SR2 |
NCBI Protein Information: | transportin-3; imp12; importin 12; limb girdle muscular dystrophy 1F (autosomal dominant); transportin-SR |
UniProt Protein Name: | Transportin-3 |
UniProt Synonym Protein Names: | Importin-12; Imp12; Transportin-SR; TRN-SR |
Protein Family: | Transportin |
UniProt Gene Name: | TNPO3 |
UniProt Entry Name: | TNPO3_HUMAN |