TNFRSF4 Antibody (PACO02256)
- SKU:
- PACO02256
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | TNFRSF4 Antibody |
抗体コード: | PACO02256 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human |
免疫原: | synthesized peptide derived from the Internal region of human Ox40. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | TNFRSF4; TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD134 |
UniProt Protein Function: | TNFRSF4: Receptor for TNFSF4/OX40L/GP34. |
UniProt Protein Details: | Protein type:Apoptosis; Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p36 Cellular Component: cell surface; integral to plasma membrane; external side of plasma membrane Molecular Function:tumor necrosis factor receptor activity Biological Process: T cell proliferation; regulation of apoptosis; tumor necrosis factor-mediated signaling pathway; negative regulation of transcription factor activity; negative regulation of cytokine secretion; positive regulation of B cell proliferation; cellular defense response; immune response; positive regulation of immunoglobulin secretion; negative regulation of transcription, DNA-dependent; inflammatory response; regulation of protein kinase activity Disease: Immunodeficiency 16 |
NCBI Summary: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008] |
UniProt Code: | P43489 |
NCBI GenInfo Identifier: | 1171933 |
NCBI Gene ID: | 7293 |
NCBI Accession: | P43489.1 |
UniProt Related Accession: | P43489 |
Molecular Weight: | |
NCBI Full Name: | Tumor necrosis factor receptor superfamily member 4 |
NCBI Synonym Full Names: | TNF receptor superfamily member 4 |
NCBI Official Symbol: | TNFRSF4 |
NCBI Official Synonym Symbols: | OX40; ACT35; CD134; IMD16; TXGP1L |
NCBI Protein Information: | tumor necrosis factor receptor superfamily member 4 |
UniProt Protein Name: | Tumor necrosis factor receptor superfamily member 4 |
UniProt Synonym Protein Names: | ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD_antigen: CD134 |
UniProt Gene Name: | TNFRSF4 |
UniProt Entry Name: | TNR4_HUMAN |