TNFRSF17 Antibody (PACO07213)
- SKU:
- PACO07213
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TNFRSF17 Antibody (PACO07213) |
抗体コード: | PACO07213 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:10000, WB:1:500-1:2000 |
反応性: | Human |
免疫原: | Synthesized peptide derived from the Internal region of human CD269. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of K562/JK using CD269 antibody. Antibody was diluted at 1:2000. Secondary antibody was diluted at 1:20000. | |
Western blot analysis of L929 293T MCF7 HELA using CD269 antibody. Antibody was diluted at 1:2000. Secondary antibody was diluted at 1:20000. |
シノニム: | TNFRSF17; BCM; BCMA; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269 |
UniProt Protein Function: | TNFRSF17: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.Protein type: Oncoprotein; Receptor, misc.; Membrane protein, integralChromosomal Location of Human Ortholog: 16p13.1Cellular Component: endomembrane system; integral to membrane; plasma membraneMolecular Function: receptor activityBiological Process: adaptive immune response; cell proliferation; lymphocyte homeostasis; multicellular organismal development; signal transduction; tumor necrosis factor-mediated signaling pathway |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q02223 |
NCBI GenInfo Identifier: | 313104029 |
NCBI Gene ID: | 608 |
NCBI Accession: | Q02223.2 |
UniProt Secondary Accession: | Q02223,Q2TQ40 |
UniProt Related Accession: | Q02223 |
Molecular Weight: | 14,843 Da |
NCBI Full Name: | Tumor necrosis factor receptor superfamily member 17 |
NCBI Synonym Full Names: | tumor necrosis factor receptor superfamily member 17 |
NCBI Official Symbol: | TNFRSF17 |
NCBI Official Synonym Symbols: | BCM; BCMA; CD269; TNFRSF13A |
NCBI Protein Information: | tumor necrosis factor receptor superfamily member 17 |
UniProt Protein Name: | Tumor necrosis factor receptor superfamily member 17 |
UniProt Synonym Protein Names: | B-cell maturation protein; CD_antigen: CD269 |
Protein Family: | |
UniProt Gene Name: | TNFRSF17 |
UniProt Entry Name: | TNR17_HUMAN |