TMEM2 Antibody (PACO60893)
- SKU:
- PACO60893
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TMEM2 Antibody (PACO60893) |
抗体コード: | PACO60893 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Cell surface hyaluronidase protein (734-866AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO60893 diluted at 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | Immunofluorescence staining of A549 cells with PACO60893 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate. |
シノニム: | Cell surface hyaluronidase (EC 3.2.1.35) (Transmembrane protein 2), TMEM2, KIAA1412 |
UniProt Protein Function: | TMEM2: May be required for the heart morphogenesis. Belongs to the TMEM2 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 9q21.13 Cellular Component: integral to membrane Biological Process: multicellular organismal development |
UniProt Code: | Q9UHN6 |
NCBI GenInfo Identifier: | 209447096 |
NCBI Gene ID: | 23670 |
NCBI Accession: | NP_001129292.1 |
UniProt Secondary Accession: | Q9UHN6,Q5T838, Q5T839, Q5T840, Q5T841, Q8NBP6, Q9P2D5 A6H8W9, B2RTQ6, |
UniProt Related Accession: | Q9UHN6 |
Molecular Weight: | 154,374 Da |
NCBI Full Name: | transmembrane protein 2 isoform b |
NCBI Synonym Full Names: | transmembrane protein 2 |
NCBI Official Symbol: | TMEM2 |
NCBI Protein Information: | transmembrane protein 2 |
UniProt Protein Name: | Transmembrane protein 2 |
Protein Family: | Transmembrane protein |
UniProt Gene Name: | TMEM2 |
UniProt Entry Name: | TMEM2_HUMAN |
Antibodies |
Anti-TMEM2 Antibody (CAB18439) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |