TMEM100 Antibody, FITC conjugated (PACO30456)
- SKU:
- PACO30456
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | TMEM100 Antibody, FITC conjugated (PACO30456) |
抗体コード: | PACO30456 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Transmembrane protein 100 protein (1-55AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex. |
シノニム: | Transmembrane protein 100, TMEM100 |
UniProt Protein Function: | TMEM100: Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Up-regulated by GDF2/BMP9 and BMP10 (at protein level)Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 17q22Cellular Component: perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane; plasma membrane; perikaryonBiological Process: BMP signaling pathway; Notch signaling pathway; positive regulation of endothelial cell differentiation; in utero embryonic development; protein kinase B signaling cascade; angiogenesis; vasculogenesis |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9NV29 |
NCBI GenInfo Identifier: | 153792480 |
NCBI Gene ID: | 55273 |
NCBI Accession: | NP_001093110.1 |
UniProt Secondary Accession: | Q9NV29,Q96FZ0, D3DTY7, I3L214 |
UniProt Related Accession: | Q9NV29 |
Molecular Weight: | 14,386 Da |
NCBI Full Name: | transmembrane protein 100 |
NCBI Synonym Full Names: | transmembrane protein 100 |
NCBI Official Symbol: | TMEM100 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | transmembrane protein 100 |
UniProt Protein Name: | Transmembrane protein 100 |
UniProt Synonym Protein Names: | |
Protein Family: | Transmembrane protein |
UniProt Gene Name: | TMEM100 |
UniProt Entry Name: | TM100_HUMAN |