TLR3 Antibody (PACO13897)
- SKU:
- PACO13897
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TLR3 Antibody (PACO13897) |
抗体コード: | PACO13897 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Fusion protein of human TLR3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO13897(TLR3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cells, Raji cells, K562 cells, Primary antibody: PACO13897(TLR3 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO13897(TLR3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. |
シノニム: | toll-like receptor 3 |
UniProt Code: | O15455 |
NCBI GenInfo Identifier: | 20140422 |
NCBI Gene ID: | 7098 |
NCBI Accession: | O15455.1 |
UniProt Secondary Accession: | O15455,Q4VAL2, Q504W0, B2RAI7, B7Z7K0, E6Y0F0, E6Y0F1 E9PGH4, |
UniProt Related Accession: | O15455 |
Molecular Weight: | 72,937 Da |
NCBI Full Name: | Toll-like receptor 3 |
NCBI Synonym Full Names: | toll like receptor 3 |
NCBI Official Symbol: | TLR3 |
NCBI Official Synonym Symbols: | CD283; IIAE2 |
NCBI Protein Information: | toll-like receptor 3 |
UniProt Protein Name: | Toll-like receptor 3 |
UniProt Synonym Protein Names: | CD_antigen: CD283 |
Protein Family: | Toll-like receptor |
UniProt Gene Name: | TLR3 |
Antibodies | ELISA Kits |
Anti-TLR3 Antibody (CAB11778) | Human Toll-like receptor 3 (TLR3) ELISA Kit |
Anti-TLR3 Antibody (CAB1449) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |