TLE4 Antibody (PACO01633)
- SKU:
- PACO01633
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TLE4 Antibody |
抗体コード: | PACO01633 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from the Internal region of human TLE4. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | TLE4; KIAA1261; Transducin-like enhancer protein 4 |
UniProt Protein Function: | TLE4: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2. Interacts with ZNF703; TLE4 may mediate ZNF703 transcriptional repression. In all tissues examined, mostly in brain, and muscle. Belongs to the WD repeat Groucho/TLE family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 9q21.31 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding |
UniProt Code: | Q04727 |
NCBI GenInfo Identifier: | 158518541 |
NCBI Gene ID: | 7091 |
NCBI Accession: | Q04727.3 |
UniProt Secondary Accession: | Q04727,Q3ZCS1, Q5T1Y2, Q6PCB3, Q9BZ07, Q9BZ08, Q9BZ09 Q9NSL3, Q9ULF9, F8W6T6, |
UniProt Related Accession: | Q04727 |
Molecular Weight: | 81,011 Da |
NCBI Full Name: | Transducin-like enhancer protein 4 |
NCBI Synonym Full Names: | transducin like enhancer of split 4 |
NCBI Official Symbol: | TLE4 |
NCBI Official Synonym Symbols: | ESG; BCE1; ESG4; GRG4; BCE-1; Grg-4; E(spI) |
NCBI Protein Information: | transducin-like enhancer protein 4 |
UniProt Protein Name: | Transducin-like enhancer protein 4 |
UniProt Synonym Protein Names: | Grg-4; Groucho-related protein 4 |
Protein Family: | Transducin-like enhancer protein |
UniProt Gene Name: | TLE4 |
UniProt Entry Name: | TLE4_HUMAN |