TIFA Antibody (PACO38706)
- SKU:
- PACO38706
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TIFA Antibody (PACO38706) |
抗体コード: | PACO38706 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human TRAF-interacting protein with FHA domain-containing protein A protein (1-184AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
バックグラウンド: | Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. |
シノニム: | TRAF-interacting protein with FHA domain-containing protein A (Putative MAPK-activating protein PM14) (Putative NF-kappa-B-activating protein 20) (TRAF2-binding protein), TIFA, T2BP |
UniProt Protein Function: | TIFA: Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.Chromosomal Location of Human Ortholog: 4q25Molecular Function: protein binding |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q96CG3 |
NCBI GenInfo Identifier: | 74751795 |
NCBI Gene ID: | 92610 |
NCBI Accession: | Q96CG3.1 |
UniProt Secondary Accession: | Q96CG3 |
UniProt Related Accession: | Q96CG3 |
Molecular Weight: | 21,445 Da |
NCBI Full Name: | TRAF-interacting protein with FHA domain-containing protein A |
NCBI Synonym Full Names: | TRAF interacting protein with forkhead associated domain |
NCBI Official Symbol: | TIFA |
NCBI Official Synonym Symbols: | T2BP; T6BP; TIFAA |
NCBI Protein Information: | TRAF-interacting protein with FHA domain-containing protein A |
UniProt Protein Name: | TRAF-interacting protein with FHA domain-containing protein A |
UniProt Synonym Protein Names: | Putative MAPK-activating protein PM14; Putative NF-kappa-B-activating protein 20; TRAF2-binding protein |
Protein Family: | TRAF-interacting protein with FHA domain-containing protein |
UniProt Gene Name: | TIFA |
UniProt Entry Name: | TIFA_HUMAN |