TFRC Antibody (PACO02062)
- SKU:
- PACO02062
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TFRC Antibody |
抗体コード: | PACO02062 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human |
免疫原: | synthesized peptide derived from the N-terminal region of human CD71. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | TFRC; Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; T9; p90; CD71 |
UniProt Protein Function: | TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. |
UniProt Protein Details: | Protein type:Receptor, misc.; Cell surface; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q29 Cellular Component: basolateral plasma membrane; cell surface; coated pit; cytoplasmic membrane-bound vesicle; endosome; external side of plasma membrane; extracellular region; extracellular space; integral to plasma membrane; intracellular membrane-bound organelle; perinuclear region of cytoplasm; plasma membrane; recycling endosome Molecular Function:double-stranded RNA binding; glycoprotein binding; identical protein binding; protein binding; protein homodimerization activity; transferrin receptor activity Biological Process: regulation of cell growth; regulation of cell proliferation; transferrin transport |
NCBI Summary: | This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015] |
UniProt Code: | P02786 |
NCBI GenInfo Identifier: | 108935939 |
NCBI Gene ID: | 7037 |
NCBI Accession: | P02786.2 |
UniProt Secondary Accession: | P02786,Q1HE24, Q59G55, Q9UCN0, Q9UCU5, Q9UDF9, Q9UK21 D3DXB0, |
UniProt Related Accession: | P02786 |
Molecular Weight: | 84,871 Da |
NCBI Full Name: | Transferrin receptor protein 1 |
NCBI Synonym Full Names: | transferrin receptor |
NCBI Official Symbol: | TFRC |
NCBI Official Synonym Symbols: | T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46 |
NCBI Protein Information: | transferrin receptor protein 1 |
UniProt Protein Name: | Transferrin receptor protein 1 |
UniProt Synonym Protein Names: | T9; p90; CD_antigen: CD71 |
Protein Family: | Transferrin receptor protein |
UniProt Gene Name: | TFRC |
UniProt Entry Name: | TFR1_HUMAN |