Tf Antibody, FITC conjugated (PACO63865)
- SKU:
- PACO63865
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Description
抗体名: | Tf Antibody, FITC conjugated (PACO63865) |
抗体コード: | PACO63865 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Mouse |
免疫原: | Recombinant Mouse Serotransferrin protein (401-697AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. |
シノニム: | Serotransferrin (Transferrin) (Beta-1 metal-binding globulin) (Siderophilin), Tf, Trf |
UniProt Protein Function: | TF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Defects in TF are the cause of atransferrinemia (ATRAF). Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Belongs to the transferrin family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Cellular Component: extracellular space; cell surface; cytoplasmic membrane-bound vesicle; early endosome; extracellular region; coated pit; recycling endosome; membrane; perinuclear region of cytoplasm; endocytic vesicle; apical plasma membrane; late endosome; basal plasma membrane; basement membrane; vesicle; endosome Molecular Function:protein binding; ferric iron binding; metal ion binding; ferric iron transmembrane transporter activity Biological Process: positive regulation of myelination; iron ion homeostasis; transport; positive regulation of transcription, DNA-dependent; actin filament organization; positive regulation of bone resorption; ion transport; osteoclast differentiation; ferric iron transport; iron ion transport; activation of JNK activity; positive regulation of phosphorylation |
UniProt Code: | Q921I1 |
NCBI GenInfo Identifier: | 20330802 |
NCBI Gene ID: | 22041 |
NCBI Accession: | NP_598738.1 |
UniProt Secondary Accession: | Q921I1,O35421, Q3UBW7, Q58E69, Q61803, Q62357, Q62358 Q62359, Q63915, Q64515, Q8VII5, Q922C0, |
UniProt Related Accession: | Q921I1 |
Molecular Weight: | 80.0 kDa |
NCBI Full Name: | serotransferrin |
NCBI Synonym Full Names: | transferrin |
NCBI Official Symbol: | Trf |
NCBI Official Synonym Symbols: | HP; Tf; Tfn; hpx; Cd176; AI266983 |
NCBI Protein Information: | serotransferrin |
UniProt Protein Name: | Serotransferrin |
UniProt Synonym Protein Names: | Beta-1 metal-binding globulin; Siderophilin |
UniProt Gene Name: | Tf |
UniProt Entry Name: | TRFE_MOUSE |