TCTN3 Antibody (PACO50666)
- SKU:
- PACO50666
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TCTN3 Antibody (PACO50666) |
抗体コード: | PACO50666 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
反応性: | Human, Rat |
免疫原: | Recombinant Human Tectonic-3 protein (348-472AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: HEK293 whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate, Rat heart tissue, Rat liver tissue, Rat stomach tissue. All lanes: TCTN3 antibody at 3.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 67, 48, 23, 51 kDa. Observed band size: 67, 51 kDa.. | |
Immunofluorescent analysis of HepG2 cells using PACO50666 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). May be involved in apoptosis regulation. Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway. |
シノニム: | Tectonic-3, TCTN3, C10orf61 TECT3 |
UniProt Protein Function: | TCTN3: Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation. Belongs to the tectonic family. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Apoptosis; Membrane protein, integral Chromosomal Location of Human Ortholog: 10q24.1 Cellular Component: integral to membrane Biological Process: smoothened signaling pathway; apoptosis; organelle organization and biogenesis Disease: Joubert Syndrome 18; Joubert Syndrome 1; Orofaciodigital Syndrome Iv |
NCBI Summary: | This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012] |
UniProt Code: | Q6NUS6 |
NCBI GenInfo Identifier: | 91208025 |
NCBI Gene ID: | 26123 |
NCBI Accession: | Q6NUS6.2 |
UniProt Secondary Accession: | Q6NUS6,Q6P7P3, Q6UW27, Q6ZQQ0, Q8N7K1, Q8NBQ0, Q96GF7 Q9Y3U1, A6NIC8, B0QZ90, B4DR81, |
UniProt Related Accession: | Q6NUS6 |
Molecular Weight: | 607 |
NCBI Full Name: | Tectonic-3 |
NCBI Synonym Full Names: | tectonic family member 3 |
NCBI Official Symbol: | TCTN3 |
NCBI Official Synonym Symbols: | OFD4; TECT3; JBTS18; C10orf61 |
NCBI Protein Information: | tectonic-3 |
UniProt Protein Name: | Tectonic-3 |
Protein Family: | Tectonic |
UniProt Gene Name: | TCTN3 |
UniProt Entry Name: | TECT3_HUMAN |