TAOK3 Antibody (PACO12637)
- SKU:
- PACO12637
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | TAOK3 Antibody (PACO12637) |
抗体コード: | PACO12637 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human TAOK3 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | TAO kinase 3;TAOK3;DKFZp666H245;DPK;FLJ31808;JIK;MAP3K18 ; |
UniProt Protein Function: | TAO3: Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress- activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF). Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. |
UniProt Protein Details: | Protein type:EC 2.7.11.1; Protein kinase, STE; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; TAO subfamily Chromosomal Location of Human Ortholog: 12q Cellular Component: cytoplasm Molecular Function:protein binding; protein kinase inhibitor activity; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity; transferase activity Biological Process: MAPKKK cascade; mitotic cell cycle G2/M transition DNA damage checkpoint; negative regulation of JNK cascade; positive regulation of JNK activity; positive regulation of JNK cascade; positive regulation of stress-activated MAPK cascade; protein amino acid autophosphorylation; protein amino acid phosphorylation; response to DNA damage stimulus |
UniProt Code: | Q9H2K8 |
NCBI GenInfo Identifier: | 78099183 |
NCBI Gene ID: | 51347 |
NCBI Accession: | Q9H2K8.2 |
UniProt Secondary Accession: | Q9H2K8,Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7, |
UniProt Related Accession: | Q9H2K8 |
Molecular Weight: | 105,406 Da |
NCBI Full Name: | Serine/threonine-protein kinase TAO3 |
NCBI Synonym Full Names: | TAO kinase 3 |
NCBI Official Symbol: | TAOK3 |
NCBI Official Synonym Symbols: | DPK; JIK; MAP3K18 |
NCBI Protein Information: | serine/threonine-protein kinase TAO3 |
UniProt Protein Name: | Serine/threonine-protein kinase TAO3 |
UniProt Synonym Protein Names: | Cutaneous T-cell lymphoma-associated antigen HD-CL-09; CTCL-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase; Jun kinase-inhibitory kinase; Kinase from chicken homolog A; hKFC-A; Thousand and one amino acid protein 3 |
Protein Family: | Serine/threonine-protein kinase |
UniProt Gene Name: | TAOK3 |
UniProt Entry Name: | TAOK3_HUMAN |