TAF6L Antibody (PACO51234)
- SKU:
- PACO51234
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TAF6L Antibody (PACO51234) |
抗体コード: | PACO51234 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L protein (345-433AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO51234 at dilution of 1:100. |
バックグラウンド: | Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. |
シノニム: | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65-alpha) (PAF65-alpha), TAF6L, PAF65A |
UniProt Protein Function: | TAF6L: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Belongs to the TAF6 family. |
UniProt Protein Details: | Protein type:Transcription initiation complex Chromosomal Location of Human Ortholog: 11q12.3 Cellular Component: histone deacetylase complex Molecular Function:DNA binding; histone acetyltransferase activity; protein binding; transcription coactivator activity Biological Process: chromatin remodeling; regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y6J9 |
NCBI GenInfo Identifier: | 46577572 |
NCBI Gene ID: | 10629 |
NCBI Accession: | Q9Y6J9.1 |
UniProt Secondary Accession: | Q9Y6J9,Q96HA6, B2RAT0, |
UniProt Related Accession: | Q9Y6J9 |
Molecular Weight: | 67,814 Da |
NCBI Full Name: | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L |
NCBI Synonym Full Names: | TATA-box binding protein associated factor 6 like |
NCBI Official Symbol: | TAF6L |
NCBI Official Synonym Symbols: | PAF65A |
NCBI Protein Information: | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L |
UniProt Protein Name: | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L |
UniProt Synonym Protein Names: | PCAF-associated factor 65-alpha; PAF65-alpha |
Protein Family: | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor |
UniProt Gene Name: | TAF6L |
UniProt Entry Name: | TAF6L_HUMAN |