SYT6 Antibody (PACO62475)
- SKU:
- PACO62475
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SYT6 Antibody (PACO62475) |
抗体コード: | PACO62475 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Synaptotagmin-6 protein (104-425AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescence staining of MCF-7 cells with PACO62475 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm (By similarity). |
シノニム: | Synaptotagmin-6 (Synaptotagmin VI) (SytVI), SYT6 |
UniProt Protein Function: | SYT6: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)- regulation of exocytosis in acrosomal reaction in sperm. Belongs to the synaptotagmin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Vesicle Chromosomal Location of Human Ortholog: 1p13.2 Cellular Component: cytosol; extrinsic to membrane; integral to membrane; plasma membrane Molecular Function:calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; protein homodimerization activity; syntaxin binding Biological Process: calcium ion-dependent exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis; vesicle fusion |
NCBI Summary: | The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q5T7P8 |
NCBI GenInfo Identifier: | 209572719 |
NCBI Gene ID: | 148281 |
NCBI Accession: | Q5T7P8.3 |
UniProt Secondary Accession: | Q5T7P8,B1AMB8, B3KPK1, |
UniProt Related Accession: | Q5T7P8 |
Molecular Weight: | 48,442 Da |
NCBI Full Name: | Synaptotagmin-6 |
NCBI Synonym Full Names: | synaptotagmin 6 |
NCBI Official Symbol: | SYT6 |
NCBI Official Synonym Symbols: | sytVI |
NCBI Protein Information: | synaptotagmin-6 |
UniProt Protein Name: | Synaptotagmin-6 |
UniProt Synonym Protein Names: | Synaptotagmin VI; SytVI |
Protein Family: | Synaptotagmin |
UniProt Gene Name: | SYT6 |
UniProt Entry Name: | SYT6_HUMAN |
Antibodies |
Anti-SYT6 Antibody (CAB16171) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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