SUOX Antibody (PACO30222)
- SKU:
- PACO30222
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SUOX Antibody (PACO30222) |
抗体コード: | PACO30222 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human, Rat |
免疫原: | Recombinant Human Sulfite oxidase, mitochondrial protein (80-545AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: SUOX antibody at 2µg/ml + Rat liver tissue Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 61 kDa Observed band size: 61 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO30222 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human liver tissue using PACO30222 at dilution of 1:100. |
バックグラウンド: | Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acid, cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. |
シノニム: | Sulfite oxidase, mitochondrial (EC 1.8.3.1), SUOX |
UniProt Protein Function: | SUOX: Defects in SUOX are the cause of isolated sulfite oxidase deficiency (ISOD); also known as sulfocysteinuria. ISOD is characterized by neurological abnormalities including multicystic leukoencephalopathy with brain atrophy. Patients often suffer from seizures. Often leads to death at an early age. |
UniProt Protein Details: | Protein type:Mitochondrial; Energy Metabolism - sulfur; Oxidoreductase; EC 1.8.3.1 Chromosomal Location of Human Ortholog: 12q13.2 Cellular Component: mitochondrial matrix; mitochondrial intermembrane space Molecular Function:molybdopterin cofactor binding; electron carrier activity; molybdenum ion binding; heme binding; sulfite oxidase activity Biological Process: sulfur amino acid metabolic process; sulfur amino acid catabolic process Disease: Sulfocysteinuria |
NCBI Summary: | Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq, Jul 2008] |
UniProt Code: | P51687 |
NCBI GenInfo Identifier: | 152031695 |
NCBI Gene ID: | 6821 |
NCBI Accession: | P51687.2 |
UniProt Related Accession: | P51687 |
Molecular Weight: | 545 |
NCBI Full Name: | Sulfite oxidase, mitochondrial |
NCBI Synonym Full Names: | sulfite oxidase |
NCBI Official Symbol: | SUOX |
NCBI Protein Information: | sulfite oxidase, mitochondrial |
UniProt Protein Name: | Sulfite oxidase, mitochondrial |
Protein Family: | Sulfite oxidase |
UniProt Gene Name: | SUOX |
UniProt Entry Name: | SUOX_HUMAN |
Antibodies | ELISA Kits |
Anti-SUOX Antibody (CAB14258) | Human Sulfite oxidase, mitochondrial (SUOX) ELISA Kit |
SUOX Antibody (PACO12586) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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