STK33 Antibody (PACO17166)
- SKU:
- PACO17166
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | STK33 Antibody (PACO17166) |
抗体コード: | PACO17166 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Fusion protein of human STK33 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17166(STK33 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17166(STK33 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | STK33 (serine/threonine kinase 33) is a 514 amino acid, protein that belongs to the CaMK (calcium/calmodulin dependent kinase) subfamily of structurally related serine/threonine kinases. Widely expressed at low levels with predominant expression in testis, lung, retina and fetal organs such as brain, heart and spinal cord, STK33 contains one protein kinase domain and functions as a Ser/Thr protein kinase with a possible role in spermatogenesis. The gene encoding STK33 lies within a region on chromosome 11 that has been associated with a variety of defects, including Long QT syndrome, T-cell leukemia, Beckwith-Wiedemann syndrome, Usher syndrome 1C and various other malignancies. |
シノニム: | serine/threonine kinase 33 |
UniProt Protein Function: | STK33: Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic behavior of the intermediate filament cytoskeleton by phosphorylation of VIME. Not essential for the survival of KRAS-dependent AML cell lines. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; CAMK-Unique family Chromosomal Location of Human Ortholog: 11p15.3 Cellular Component: perinuclear region of cytoplasm Molecular Function:protein serine/threonine kinase activity; ATP binding Biological Process: protein amino acid autophosphorylation |
UniProt Code: | Q9BYT3 |
NCBI GenInfo Identifier: | 74761329 |
NCBI Gene ID: | 65975 |
NCBI Accession: | Q9BYT3.1 |
UniProt Secondary Accession: | Q9BYT3,Q658S6, Q8NEF5, |
UniProt Related Accession: | Q9BYT3 |
Molecular Weight: | 514 |
NCBI Full Name: | Serine/threonine-protein kinase 33 |
NCBI Synonym Full Names: | serine/threonine kinase 33 |
NCBI Official Symbol: | STK33 |
NCBI Protein Information: | serine/threonine-protein kinase 33 |
UniProt Protein Name: | Serine/threonine-protein kinase 33 |
Protein Family: | Serine/threonine-protein kinase |
UniProt Gene Name: | STK33 |
UniProt Entry Name: | STK33_HUMAN |